Frazer Kelly A相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

A highly accurate risk factor-based XGBoost multiethnic model for identifying patients with skin cancer

一种基于风险因素的高精度XGBoost多民族模型，用于识别皮肤癌患者

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-64556-y

D'Antonio, Matteo; G Gonzalez Rivera, Wilfredo; Greenes, Robert A; Gymrek, Melissa; Frazer, Kelly A

发表日期：2025

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Human Variant in the Cardiac Troponin I Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model

人类心脏肌钙蛋白I转换结构域变异导致新型小鼠模型出现舒张功能障碍

期刊:Journal of the American Heart Association

影响因子:5.3

doi:10.1161/JAHA.125.040852

Silver, Elizabeth; Duran, Jason M; Gunes, Betul Beyza; Fenwick, Axel J; Maisel, Sofie; Wang, Tsui-Min; Manso, Ana Maria; Cruz, Marina Sampaio; Gu, Yusu; Fong, Joshua; Shathaya, Aysen; Chen, Chao; Soto-Hermida, Angel; Feng, Wei; Cho, Yoshitake; Bogomolovas, Julius; Gelow, Jill M; Masri, Ahmad; Frazer, Kelly A; Ross, Robert S; Chen, Ju; Makarewich, Catherine A; Cammarato, Anthony; McCulloch, Andrew D; Bushway, Paul; Adler, Eric D

发表日期：2025

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Genetic analysis of elevated levels of creatinine and cystatin C biomarkers reveals novel genetic loci associated with kidney function

对肌酐和胱抑素C生物标志物水平升高进行基因分析，揭示了与肾功能相关的新基因位点。

期刊:Human Molecular Genetics

影响因子:3.2

doi:10.1093/hmg/ddaf018

D'Antonio, Matteo; Arthur, Timothy D; Gonzalez Rivera, Wilfredo G; Wu, Ximei; Nguyen, Jennifer P; Gymrek, Melissa; Woo-Yeong, Park; Frazer, Kelly A

发表日期：2025

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IFNγ activates an immune-like regulatory network in the cardiac vascular endothelium

IFNγ激活心脏血管内皮细胞中的免疫样调节网络。

期刊:Journal of Molecular and Cellular Cardiology Plus

影响因子:2.2

doi:10.1016/j.jmccpl.2025.100289

Arthur, Timothy D; Joshua, Isaac N; Nguyen, Jennifer P; D'Antonio-Chronowska, Agnieszka; D'Antonio, Matteo; Frazer, Kelly A

细胞生物学

免疫/内分泌

发表日期：2025

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Characterization of shared and ancestry-specific signals driving complex traits using multi-ancestry fine-mapping

利用多祖源精细定位技术，对驱动复杂性状的共享信号和祖源特异性信号进行表征

doi:10.1101/2025.11.13.25339614

Mirmira, Tara; Ma, Nichole; Margoliash, Jonathan; Rivera, Wilfredo G Gonzalez; Amariuta, Tiffany; Frazer, Kelly A; Goren, Alon; Gymrek, Melissa

发表日期：2025

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Admixture mapping identifies complex trait associations with local ancestry in the All of Us Research Program

混合映射分析揭示了“我们所有人”研究计划中复杂性状与当地祖先的关联。

doi:10.64898/2025.12.29.25343152

Gonzalez Rivera, Wilfredo G; Liu, Youwen; Mirmira, Tara; Ma, Nichole; Kim, Jihoon; D' Antonio, Matteo; Dube, Umber; Frazer, Kelly A; Gymrek, Melissa

发表日期：2025

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Genetics of growth rate in induced pluripotent stem cells.

诱导多能干细胞生长速率的遗传学研究

doi:10.1101/2025.07.02.662844

Lee Brian N, Taylor Henry J, Cipriani Filippo, Narisu Narisu, Robertson Catherine C, Swift Amy J, Sinha Neelam, Yan Tingfen, Bonnycastle Lori L, Dale Nathan, Butt Annie, Parsaud Hemant, Semrau Stefan, Knowles Joshua W, Carcamo-Orive Ivan, D'Antonio-Chronowska Agnieszka, Frazer Kelly A, Biesecker Leslie G, Noggle Scott, Erdos Michael R, Paull Daniel, Collins Francis S, Taylor D Leland

发育与干细胞

细胞生物学

发表日期：2025

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Complex regulatory networks influence pluripotent cell state transitions in human iPSCs

复杂的调控网络影响人类诱导多能干细胞的多能性状态转变

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-45506-6

Arthur, Timothy D; Nguyen, Jennifer P; D'Antonio-Chronowska, Agnieszka; Matsui, Hiroko; Silva, Nayara S; Joshua, Isaac N; Luchessi, André D; Greenwald, William W Young; D'Antonio, Matteo; Pera, Martin F; Frazer, Kelly A

细胞生物学

发育与干细胞

发表日期：2024

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Multi-omic QTL mapping in early developmental tissues reveals phenotypic and temporal complexity of regulatory variants underlying GWAS loci

早期发育组织中的多组学QTL定位揭示了GWAS位点潜在调控变异的表型和时间复杂性

doi:10.1101/2024.04.10.588874

Arthur, Timothy D; Nguyen, Jennifer P; D'Antonio-Chronowska, Agnieszka; Jaureguy, Jeffrey; Silva, Nayara; Henson, Benjamin; Panopoulos, Athanasia D; Belmonte, Juan Carlos Izpisua; D'Antonio, Matteo; McVicker, Graham; Frazer, Kelly A

发育与干细胞

发表日期：2024

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Recruitment of CTCF to the SIRT1 promoter after Oxidative Stress mediates Cardioprotective Transcription

氧化应激后CTCF募集至SIRT1启动子介导心脏保护性转录

doi:10.1101/2024.05.17.594600

Wagner, Tobias; Priyanka, Priyanka; Micheletti, Rudi; Friedman, Meyer J; Nair, Sreejith J; Gamliel, Amir; Taylor, Havilah; Song, Xiaoyuan; Cho, Miook; Oh, Soohwan; Li, Wenbo; Han, Jeehae; Ohgi, Kenneth A; Abrass, Madeline; D'Antonio-Chronowska, Agnieszka; D'Antonio, Matteo; Hazuda, Helen; Duggirala, Ravindranath; Blangero, John; Ding, Sheng; Guzmann, Carlos; Frazer, Kelly A; Aggarwal, Aneel K; Zemljic-Harpf, Alice E; Rosenfeld, Michael G; Suh, Yousin

发表日期：2024

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