日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Role of YAP in early ectodermal specification and a Huntington's Disease model of human neurulation

YAP在早期外胚层分化中的作用以及亨廷顿病人类神经管形成模型

Francesco M Piccolo #,Nathaniel R Kastan # ,Tomomi Haremaki,Qingyun Tian,Tiago L Laundos   ,Riccardo De Santis,Andrew J Beaudoin,Thomas S Carroll,Ji-Dung Luo,Ksenia Gnedeva ,Fred Etoc,A J Hudspeth # ,Ali H Brivanlou #

Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models

基于微模式的类器官的深度学习分析可实现亨廷顿病模型的高通量药物筛选

Jakob J Metzger ,Carlota Pereda ,Arjun Adhikari ,Tomomi Haremaki ,Szilvia Galgoczi ,Eric D Siggia ,Ali H Brivanlou ,Fred Etoc

Self-organization of human dorsal-ventral forebrain structures by light induced SHH

人类背腹前脑结构通过光诱导的SHH进行自组织

Riccardo De Santis, Fred Etoc, Edwin A Rosado-Olivieri, Ali H Brivanlou

Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport

BMP4/NOGGIN 的差异化区域化需要 NOGGIN 跨上皮运输

Tien Phan-Everson, Fred Etoc, Shu Li, Samuel Khodursky, Anna Yoney, Ali H Brivanlou, Eric D Siggia

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects

亨廷顿蛋白CAG扩增通过极性缺陷损害了合成人类二维类原肠胚中的胚层模式

Szilvia Galgoczi, Albert Ruzo, Christian Markopoulos, Anna Yoney, Tien Phan-Everson, Shu Li, Tomomi Haremaki, Jakob J Metzger, Fred Etoc, Ali H Brivanlou

Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment

自组织神经样模型可模拟亨廷顿氏病在外胚层中的发育情况

Tomomi Haremaki, Jakob J Metzger, Tiago Rito, M Zeeshan Ozair, Fred Etoc, Ali H Brivanlou

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

ACTIVIN 需要 WNT 信号记忆才能在人类类原肠胚中发挥形态发生素的作用

Anna Yoney, Fred Etoc, Albert Ruzo, Thomas Carroll, Jakob J Metzger, Iain Martyn, Shu Li, Christoph Kirst, Eric D Siggia, Ali H Brivanlou

Self-organization of human embryonic stem cells on micropatterns

人类胚胎干细胞在微图案上的自组织

Alessia Deglincerti, Fred Etoc, M Cecilia Guerra, Iain Martyn, Jakob Metzger, Albert Ruzo, Mijo Simunovic, Anna Yoney, Ali H Brivanlou, Eric Siggia, Aryeh Warmflash