日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation

从成功到成功上市:精准发现和开发咪唑并嘧啶 TLR7/8 激动剂佐剂配方

Dheeraj Soni, Francesco Borriello, David A Scott, Frederic Feru, Maria DeLeon, Spencer E Brightman, Wing Ki Cheng, Gandolina Melhem, Jennifer A Smith, Juan C Ramirez, Soumik Barman, Michael Cameron, Aisling Kelly, Kristina Walker, Etsuro Nanishi, Simon Daniel van Haren, Tony Phan, Yizhi Qi, Robert K

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

探索致癌基因KRASG12C的靶向降解策略

Mei Zeng, Yuan Xiong, Nozhat Safaee, Radosław P Nowak, Katherine A Donovan, Christine J Yuan, Behnam Nabet, Thomas W Gero, Frederic Feru, Lianbo Li, Sudershan Gondi, Lincoln J Ombelets, Chunshan Quan, Pasi A Jänne, Milka Kostic, David A Scott, Kenneth D Westover, Eric S Fischer, Nathanael S Gray

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

强效、选择性的 KRAS G12C 共价喹唑啉抑制剂

Mei Zeng, Jia Lu, Lianbo Li, Frederic Feru, Chunshan Quan, Thomas W Gero, Scott B Ficarro, Yuan Xiong, Chiara Ambrogio, Raymond M Paranal, Marco Catalano, Jay Shao, Kwok-Kin Wong, Jarrod A Marto, Eric S Fischer, Pasi A Jänne, David A Scott, Kenneth D Westover, Nathanael S Gray