日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hepatocyte mitochondrial NAD(+) content is limiting for liver regeneration.

肝细胞线粒体 NAD(+) 含量限制了肝脏再生。

Mukherjee Sarmistha, Velázquez Aponte Ricardo A, Perry Caroline E, Lee Won Dong, Janssen Kevin A, Niere Marc, Adzika Gabriel K, Lu Mu-Jie, Chan Hsin-Ru, Zou Xiangyu, Chen Beishan, Bye Nicole, Xiao Teresa, Yook Jin-Seon, Salik Oniel, Frederick David W, Gaspar Ryan B, Doan Khanh V, Davis James G, Rabinowitz Joshua D, Wallace Douglas C, Snyder Nathaniel W, Kajimura Shingo, Cambronne Xiaolu A, Ziegler Mathias, Baur Joseph A

Cardiac NAD(+) depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics

小鼠心脏中 NAD(+) 耗竭会促进肥厚型心肌病和心律失常,随后才会出现生物能量学障碍。

Doan, Khanh V; Luongo, Timothy S; Ts'olo, Thato T; Lee, Won Dong; Frederick, David W; Mukherjee, Sarmistha; Adzika, Gabriel K; Perry, Caroline E; Gaspar, Ryan B; Walker, Nicole; Blair, Megan C; Bye, Nicole; Davis, James G; Holman, Corey D; Chu, Qingwei; Wang, Lin; Rabinowitz, Joshua D; Kelly, Daniel P; Cappola, Thomas P; Margulies, Kenneth B; Baur, Joseph A

Imaging Redox State in Mouse Muscles of Different Ages

不同年龄小鼠肌肉氧化还原状态成像

Moon, Lily; Frederick, David W; Baur, Joseph A; Li, Lin Z

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

性别、压力和能量摄入对小鼠衰老标志的影响

Mitchell, Sarah J; Madrigal-Matute, Julio; Scheibye-Knudsen, Morten; Fang, Evandro; Aon, Miguel; González-Reyes, José A; Cortassa, Sonia; Kaushik, Susmita; Gonzalez-Freire, Marta; Patel, Bindi; Wahl, Devin; Ali, Ahmed; Calvo-Rubio, Miguel; Burón, María I; Guiterrez, Vincent; Ward, Theresa M; Palacios, Hector H; Cai, Huan; Frederick, David W; Hine, Christopher; Broeskamp, Filomena; Habering, Lukas; Dawson, John; Beasley, T Mark; Wan, Junxiang; Ikeno, Yuji; Hubbard, Gene; Becker, Kevin G; Zhang, Yongqing; Bohr, Vilhelm A; Longo, Dan L; Navas, Placido; Ferrucci, Luigi; Sinclair, David A; Cohen, Pinchas; Egan, Josephine M; Mitchell, James R; Baur, Joseph A; Allison, David B; Anson, R Michael; Villalba, José M; Madeo, Frank; Cuervo, Ana Maria; Pearson, Kevin J; Ingram, Donald K; Bernier, Michel; de Cabo, Rafael

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.

NAD稳态丧失会导致骨骼肌进行性、可逆性退化

Frederick David W, Loro Emanuele, Liu Ling, Davila Antonio Jr, Chellappa Karthikeyani, Silverman Ian M, Quinn William J 3rd, Gosai Sager J, Tichy Elisia D, Davis James G, Mourkioti Foteini, Gregory Brian D, Dellinger Ryan W, Redpath Philip, Migaud Marie E, Nakamaru-Ogiso Eiko, Rabinowitz Joshua D, Khurana Tejvir S, Baur Joseph A

Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?

3-羟基十四碳烯酸的积累:是胰岛β细胞生物能量糖脂毒性损伤的原因还是结果?

Doliba, Nicolai M; Liu, Qing; Li, Changhong; Chen, Jie; Chen, Pan; Liu, Chengyang; Frederick, David W; Baur, Joseph A; Bennett, Michael J; Naji, Ali; Matschinsky, Franz M