Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer
选择性 CDK7 抑制可抑制细胞周期进程和 MYC 信号传导,同时增强治疗抵抗性雌激素受体阳性乳腺癌的细胞凋亡
期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-23-2975
Cristina Guarducci #, Agostina Nardone #, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Mathew Joseph Leventhal, Avery Feit, Gabriella Cohen Feit, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio
信号转导
细胞生物学
肿瘤
乳腺癌
其它细胞
Apoptosis