日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Methylation array signals are predictive of chronological age without bisulfite conversion

甲基化阵列信号无需亚硫酸氢盐转化即可预测实际年龄。

Porter, Hunter L; Ansere, Victor A; Undi, Ram Babu; Hoolehan, Walker; Giles, Cory B; Brown, Chase A; Stanford, David; Huycke, Mark M; Freeman, Willard M; Wren, Jonathan D

Necroptosis induced by MLKL overexpression in liver triggers cellular senescence and leads to chronic inflammation and fibrosis

肝脏中MLKL过表达诱导的坏死性凋亡会引发细胞衰老,并导致慢性炎症和纤维化。

Selvarani, Ramasamy; Lee, Sunho; Saminathan, Mani; Boovalingam, Puvarajan; Kurup, Kavitha; Pham, Kevin; Wolf, Roman F; Freeman, Willard M; Unnikrishnan, Archana; Richardson, Arlan

A satellite cell-dependent epigenetic fingerprint in skeletal muscle identity genes after lifelong physical activity

终生体育活动后骨骼肌身份基因中卫星细胞依赖的表观遗传指纹

Murach, Kevin A; Englund, Davis A; Chambers, Toby L; Dungan, Cory M; Porter, Hunter L; Wren, Jonathan D; Freeman, Willard M; Dupont-Versteegden, Esther E; Wen, Yuan

Late-Life Short-Term Dietary Restriction Improves Intestinal Stem Cell Function and Alters Intestinal Stem Cell Deoxyribonucleic Acid Methylation in Mice

晚年短期饮食限制可改善小鼠肠道干细胞功能并改变肠道干细胞脱氧核糖核酸甲基化

Kurup, Kavitha; Chan, Michael; Moore, Eric; Ranjo-Bishop, Michelle; Pham, Kevin; Stanford, David R; Freeman, Willard M; Unnikrishnan, Archana

Protocol to sequentially isolate mouse oligodendrocytes, microglia, endothelial cells, astrocytes, and neurons via magnetic cell sorting

利用磁性细胞分选法依次分离小鼠少突胶质细胞、小胶质细胞、内皮细胞、星形胶质细胞和神经元的方案

Houmam, Samah; Siodlak, Dominika; Pham, Kevin D; Salinas-Salinas, Casandra; Ocañas, Sarah R; Freeman, Willard M; Rice, Heather C

Hepatocyte MLKL Drives Obesity-Driven Hepatocellular Carcinoma Progression via Mitochondrial Dysfunction Independent of Necroptosis in MASLD

在MASLD中,肝细胞MLKL通过线粒体功能障碍驱动肥胖相关的肝细胞癌进展,且该过程独立于坏死性凋亡。

Ohene-Marfo, Phoebe; Mohammed, Sabira; Jiang, Chao; Bhaskaran, Shylesh; Georgescu, Constantin; John, Megan; Pham, Kevin; Tran, Albert; Rao, Chinthalapally V; Gyu Oh, Tae; Kinter, Michael; Freeman, Willard M; Houchen, Courtney; Wren, Jonathan D; Deepa, Sathyaseelan S

Protocol to isolate oligodendrocytes, microglia, endothelial cells, astrocytes, and neurons from a single mouse brain using magnetic-activated cell sorting.

利用磁激活细胞分选技术从单个小鼠脑中分离少突胶质细胞、小胶质细胞、内皮细胞、星形胶质细胞和神经元的方案

Houmam Samah, Siodlak Dominika, Pham Kevin D, Salinas-Salinas Casandra, Ocañas Sarah R, Freeman Willard M, Rice Heather C

Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans

在小鼠模型和人类中,小胶质细胞MHC-I的诱导与衰老和阿尔茨海默病相关,且这种现象是保守的。

Kellogg, Collyn M; Pham, Kevin; Machalinski, Adeline H; Porter, Hunter L; Blankenship, Harris E; Tooley, Kyla B; Stout, Michael B; Rice, Heather C; Sharpe, Amanda L; Beckstead, Michael J; Chucair-Elliott, Ana J; Ocañas, Sarah R; Freeman, Willard M

Correction to: Microglial MHC‑I induction with aging and Alzheimer's is conserved in mouse models and humans

更正:小鼠模型和人类中,小胶质细胞MHC-I的诱导与衰老和阿尔茨海默病相关,且该现象保守。

Kellogg, Collyn M; Pham, Kevin; Machalinski, Adeline H; Porter, Hunter L; Blankenship, Harris E; Tooley, Kyla B; Stout, Michael B; Rice, Heather C; Sharpe, Amanda L; Beckstead, Michael J; Chucair-Elliott, Ana J; Ocañas, Sarah R; Freeman, Willard M

Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques

评估雄性恒河猴对17α-雌二醇给药的耐受性和生理反应

Stout, Michael B; Vaughan, Kelli L; Isola, Jose V V; Mann, Shivani N; Wellman, Bayli; Hoffman, Jessica M; Porter, Hunter L; Freeman, Willard M; Mattison, Julie A