日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study

接受化疗或其他抗癌治疗的癌症患者的 COVID-19 死亡率:一项前瞻性队列研究

Lee, Lennard Yw; Cazier, Jean-Baptiste; Angelis, Vasileios; Arnold, Roland; Bisht, Vartika; Campton, Naomi A; Chackathayil, Julia; Cheng, Vinton Wt; Curley, Helen M; Fittall, Matthew W; Freeman-Mills, Luke; Gennatas, Spyridon; Goel, Anshita; Hartley, Simon; Hughes, Daniel J; Kerr, David; Lee, Alvin Jx; Lee, Rebecca J; McGrath, Sophie E; Middleton, Christopher P; Murugaesu, Nirupa; Newsom-Davis, Thomas; Okines, Alicia Fc; Olsson-Brown, Anna C; Palles, Claire; Pan, Yi; Pettengell, Ruth; Powles, Thomas; Protheroe, Emily A; Purshouse, Karin; Sharma-Oates, Archana; Sivakumar, Shivan; Smith, Ashley J; Starkey, Thomas; Turnbull, Chris D; Várnai, Csilla; Yousaf, Nadia; Kerr, Rachel; Middleton, Gary

Expression of Idh1(R132H) in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

小鼠脑室下区干细胞微环境中 Idh1(R132H) 的表达重现了早期胶质瘤发生的特征

Bardella, Chiara; Al-Dalahmah, Osama; Krell, Daniel; Brazauskas, Pijus; Al-Qahtani, Khalid; Tomkova, Marketa; Adam, Julie; Serres, Sébastien; Lockstone, Helen; Freeman-Mills, Luke; Pfeffer, Inga; Sibson, Nicola; Goldin, Robert; Schuster-Böeckler, Benjamin; Pollard, Patrick J; Soga, Tomoyoshi; McCullagh, James S; Schofield, Christopher J; Mulholland, Paul; Ansorge, Olaf; Kriaucionis, Skirmantas; Ratcliffe, Peter J; Szele, Francis G; Tomlinson, Ian

Five endometrial cancer risk loci identified through genome-wide association analysis

通过全基因组关联分析确定五个子宫内膜癌风险位点

Timothy Ht Cheng #, Deborah J Thompson #, Tracy A O'Mara, Jodie N Painter, Dylan M Glubb, Susanne Flach, Annabelle Lewis, Juliet D French, Luke Freeman-Mills, David Church, Maggie Gorman, Lynn Martin; National Study of Endometrial Cancer Genetics Group (NSECG); Shirley Hodgson, Penelope M Webb; Aust

Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibition

对按分子分类的高风险子宫内膜癌进行免疫学分析,确定 POLE 突变和微卫星不稳定癌是检查点抑制的候选对象

Florine A Eggink, Inge C Van Gool, Alexandra Leary, Pamela M Pollock, Emma J Crosbie, Linda Mileshkin, Ekaterina S Jordanova, Julien Adam, Luke Freeman-Mills, David N Church, Carien L Creutzberg, Marco De Bruyn, Hans W Nijman, Tjalling Bosse

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

异常上皮 GREM1 表达引发干细胞微环境外细胞的结肠肿瘤发生

Hayley Davis #, Shazia Irshad #, Mukesh Bansal, Hannah Rafferty, Tatjana Boitsova, Chiara Bardella, Emma Jaeger, Annabelle Lewis, Luke Freeman-Mills, Francesc Castro Giner, Pedro Rodenas-Cuadrado, Sreelakshmi Mallappa, Susan Clark, Huw Thomas, Rosemary Jeffery, Richard Poulsom, Manuel Rodriguez-Just

POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

POLE 校对突变引发子宫内膜癌的抗肿瘤免疫反应

Inge C van Gool, Florine A Eggink, Luke Freeman-Mills, Ellen Stelloo, Emanuele Marchi, Marco de Bruyn, Claire Palles, Remi A Nout, Cor D de Kroon, Elisabeth M Osse, Paul Klenerman, Carien L Creutzberg, Ian Pm Tomlinson, Vincent Thbm Smit, Hans W Nijman, Tjalling Bosse #, David N Church #

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding

GREM1 附近的多态性增强子通过差异 CDX2 和 TCF7L2 结合影响肠癌风险

Annabelle Lewis, Luke Freeman-Mills, Elisa de la Calle-Mustienes, Rosa María Giráldez-Pérez, Hayley Davis, Emma Jaeger, Martin Becker, Nina C Hubner, Luan N Nguyen, Jorge Zeron-Medina, Gareth Bond, Hendrik G Stunnenberg, Jaime J Carvajal, Jose Luis Gomez-Skarmeta, Simon Leedham, Ian Tomlinson

Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism

核苷酸合成受神经发育和适应性代谢过程中细胞蛇的形成调控

Gabriel N Aughey, Stuart J Grice, Qing-Ji Shen, Yichi Xu, Chia-Chun Chang, Ghows Azzam, Pei-Yu Wang, Luke Freeman-Mills, Li-Mei Pai, Li-Ying Sung, Jun Yan, Ji-Long Liu