日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 1b/2 study of cabozantinib in combination with pembrolizumab in advanced cutaneous melanoma

卡博替尼联合帕博利珠单抗治疗晚期皮肤黑色素瘤的 1b/2 期研究

Zakharia, Yousef; Kim, Donghyun; Freesmeier, Michele; Frees, Melanie; Mott, Sarah; Monga, Varun; Laux, Douglas; Javed, Asad; Rieth, John; Smestad, John; Milhem, Mohammed

A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition

FAK信号通路在Rac1驱动的黑色素瘤细胞对MAPK通路抑制的耐药性中起关键作用

Jesse D Riordan,Teagan A Nathanson,Afshin Varzavand,Adeline A Hawkins,Rebekah M Peplinski,Elizabeth C Hannan,Faith A Bibeau,Nathaniel J Freesmeier,Madison C Jilek,Silvia Coma,Jonathan A Pachter,Adam J Dupuy,Christopher S Stipp

Exceptional responses with sequential metronomic temozolomide after pembrolizumab failure in patients with metastatic melanoma

在转移性黑色素瘤患者中,帕博利珠单抗治疗失败后,序贯节拍式替莫唑胺治疗取得了显著疗效。

Swami, Umang; Monga, Varun; Freesmeier, Michele; Zhang, Weizhou; Bossler, Aaron D; Zakharia, Yousef; Milhem, Mohammed

Targeting epigenetics for treatment of BRAF mutated metastatic melanoma with decitabine in combination with vemurafenib: A phase lb study

针对表观遗传学,使用地西他滨联合维莫非尼治疗 BRAF 突变转移性黑色素瘤:一项 lb 期研究

Yousef Zakharia, Varun Monga, Umang Swami, Aaron D Bossler, Michele Freesmeier, Melanie Frees, Mirza Khan, Noah Frydenlund, Rithu Srikantha, Marion Vanneste, Michael Henry, Mohammed Milhem