Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma
在化学诱导的小鼠口腔鳞状细胞癌模型中,厄洛替尼抑制EGFR-STAT3信号通路可预防癌变。
期刊:Cancer Prevention Research
影响因子:2.6
doi:10.1158/1940-6207.CAPR-10-0249
Leeman-Neill, Rebecca J; Seethala, Raja R; Singh, Shivendra V; Freilino, Maria L; Bednash, Joseph S; Thomas, Sufi M; Panahandeh, Mary C; Gooding, William E; Joyce, Sonali C; Lingen, Mark W; Neill, Daniel B; Grandis, Jennifer R
肿瘤
肿瘤免疫
JAK/STAT
信号转导
EGF
STAT3
EGFR
细胞生物学