Freimoser相关文献与解析，生知库 | 链接生命科学的每一步

Marlena Surowka ，Diana Darowski ，Idil Hutter-Karakoc ，Christina Claus ，Claudia Ferrara-Koller ，Anne Freimoser-Grundschober ，Thomas Hofer ，Johannes Sam ，Reto Gianotti ，Andrzej Sobieniecki ，Denis Assisi ，John Challier ，Stephane Leclair ，Ekkehard Mössner ，Maria Amann ，Pablo Umaña ，Christian Klein

免疫/内分泌

ENG

AGER

发表日期：2026

文献求助收藏

Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs

优化T细胞双特异性抗体的疗效和安全性：FOLR1和CEACAM5 2+1 TCB中CD3和肿瘤抗原结合亲和力的相互依赖性

期刊:MAbs

影响因子:7.3

doi:10.1080/19420862.2025.2584374

Abdelmotaleb, Omar; Schneider, Anneliese; Waldhauer, Inja; Sam, Johannes; Hofer, Thomas; Lechmann, Martin; Freimoser-Grundschober, Anne; Giusti, Anna Maria; Essig, Katharina; Nikic, Tijana; Steinacher, Linda; Gassner, Christian; Märsch, Stephan; Bransi, Ali; Odermatt, Alex; Brünker, Peter; Colombetti, Sara; Klein, Christian

Microbial pesticides - challenges and future perspectives for testing and safety assessment with respect to human health

微生物农药——在人类健康方面，测试和安全性评估面临的挑战和未来展望

期刊:Environmental Health

影响因子:5.9

doi:10.1186/s12940-024-01090-2

Wend, K; Zorrilla, L; Freimoser, F M; Gallet, A

微生物学

发表日期：2024

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Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure

对T细胞结合双特异性抗体cibisatamab的抗药抗体反应进行表征，以了解其对药物暴露的影响

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2024.1406353

Lotz, Gregor P; Lutz, Achim; Martin-Facklam, Meret; Hansbauer, Andre; Schick, Eginhard; Moessner, Ekkehard; Antony, Michael; Stuchly, Thomas; Viert, Maria; Hosse, Ralf J; Freimoser-Grundschober, Anne; Klein, Christian; Schäfer, Martin; Ritter, Mirko; Stubenrauch, Kay-Gunnar

Heterologous pulcherrimin production in Saccharomyces cerevisiae confers inhibitory activity on Botrytis conidiation

在酿酒酵母中异源表达的pulcherrimin可抑制灰霉菌分生孢子的形成。

期刊:FEMS Yeast Research

影响因子:2.7

doi:10.1093/femsyr/foad053

Freimoser, Florian M; Mahler, Marina; McCullough, Mark; Brachmann, Alexander O; Nägeli, Lukas; Hilber-Bodmer, Maja; Piel, Jörn; Hoffmann, Stefan A; Cai, Yizhi

发表日期：2024

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Clinical Aureobasidium Isolates Are More Fungicide Sensitive than Many Agricultural Isolates

临床分离的黑曲霉菌株比许多农业分离株对杀菌剂更敏感

期刊:Microbiology Spectrum

影响因子:3.8

doi:10.1128/spectrum.05299-22

Magoye, Electine; Nägeli, Lukas; Bühlmann, Andreas; Hilber-Bodmer, Maja; Keller, Peter; Mühlethaler, Konrad; Riat, Arnaud; Schrenzel, Jacques; Freimoser, Florian M

发表日期：2023

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Pantothenate Auxotrophy in a Naturally Occurring Biocontrol Yeast

天然生物防治酵母中的泛酸营养缺陷型

期刊:Applied and Environmental Microbiology

影响因子:3.7

doi:10.1128/aem.00884-23

Rueda-Mejia, Maria Paula; Bühlmann, Andreas; Ortiz-Merino, Raúl A; Lutz, Stefanie; Ahrens, Christian H; Künzler, Markus; Freimoser, Florian M

Yeast

发表日期：2023

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Genome sequence data of the strongly antagonistic yeast Pichia kluyveri isolate APC 11.10 B as a foundation for analysing biocontrol mechanisms

以强拮抗酵母克鲁维毕赤酵母分离株APC 11.10 B的基因组序列数据为基础，分析其生物防治机制

期刊:Data in Brief

影响因子:1.4

doi:10.1016/j.dib.2023.109394

Nägeli, Lukas; Schuler, Martin; Segessemann, Tina; Frei, Daniel; Frey, Jürg E; Wolfe, Kenneth H; Ahrens, Christian H; Freimoser, Florian M

APC

发表日期：2023

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Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors

嵌合抗原受体 T 细胞经过改造，可识别效应沉默肿瘤抗原靶向人 IgG1 抗体的 P329G 突变 Fc 部分，从而实现对实体肿瘤的模块化靶向

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2022-005054

Sophia Stock #, Mohamed-Reda Benmebarek #, Anna-Kristina Kluever, Diana Darowski, Christian Jost, Kay-Gunnar Stubenrauch, Joerg Benz, Anne Freimoser-Grundschober, Ekkehard Moessner, Pablo Umana, Marion Subklewe, Stefan Endres, Christian Klein, Sebastian Kobold

JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy

JAK和mTOR抑制剂可阻止细胞因子释放，同时保持T细胞双特异性抗体的体内疗效。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2021-003766

Gabrielle Leclercq ，Hélène Haegel ，Alberto Toso ，Tina Zimmermann ，Luke Green ，Nathalie Steinhoff ，Johannes Sam ，Vesna Pulko ，Anneliese Schneider ，Anna Maria Giusti ，John Challier ，Anne Freimoser-Grundschober ，Laurent Larivière ，Alex Odermatt ，Martin Stern ，Pablo Umana ，Marina Bacac ，Christian Klein

P329G-engager: a universal mix & match antibody-based adaptor platform for cancer immunotherapy

P329G-engager：一种用于癌症免疫治疗的通用型抗体基接头平台，可进行多种组合搭配。

Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs

优化T细胞双特异性抗体的疗效和安全性：FOLR1和CEACAM5 2+1 TCB中CD3和肿瘤抗原结合亲和力的相互依赖性

Microbial pesticides - challenges and future perspectives for testing and safety assessment with respect to human health

微生物农药——在人类健康方面，测试和安全性评估面临的挑战和未来展望

Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure

对T细胞结合双特异性抗体cibisatamab的抗药抗体反应进行表征，以了解其对药物暴露的影响

Heterologous pulcherrimin production in Saccharomyces cerevisiae confers inhibitory activity on Botrytis conidiation

在酿酒酵母中异源表达的pulcherrimin可抑制灰霉菌分生孢子的形成。

Clinical Aureobasidium Isolates Are More Fungicide Sensitive than Many Agricultural Isolates

临床分离的黑曲霉菌株比许多农业分离株对杀菌剂更敏感

Pantothenate Auxotrophy in a Naturally Occurring Biocontrol Yeast

天然生物防治酵母中的泛酸营养缺陷型

Genome sequence data of the strongly antagonistic yeast Pichia kluyveri isolate APC 11.10 B as a foundation for analysing biocontrol mechanisms

以强拮抗酵母克鲁维毕赤酵母分离株APC 11.10 B的基因组序列数据为基础，分析其生物防治机制

Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors

嵌合抗原受体 T 细胞经过改造，可识别效应沉默肿瘤抗原靶向人 IgG1 抗体的 P329G 突变 Fc 部分，从而实现对实体肿瘤的模块化靶向

JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy

JAK和mTOR抑制剂可阻止细胞因子释放，同时保持T细胞双特异性抗体的体内疗效。