日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effects of ribonucleotides on telomeric G4 formation, dynamics, and initiation of ribonucleotide excision repair by RNase H2

核糖核苷酸对端粒G4形成、动态变化以及RNase H2介导的核糖核苷酸切除修复起始的影响

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1501
Cortez, Luis M; Rahman, Md Ibnul Rifat; Welfer, Griffin A; Riva, Fillipo; Buettner, Kristen J; Lee, Hui-Ting; Freudenthal, Bret D
发表日期：2026
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Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β

DNA聚合酶β在核小体中进行缺口填充DNA合成的结构基础

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57915-2
Weaver, Tyler M; Ryan, Benjamin J; Thompson, Spencer H; Hussen, Adil S; Spencer, Jonah J; Xu, Zhen; Schnicker, Nicholas J; Freudenthal, Bret D
发表日期：2025
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The zinc finger of DNA ligase 3α binds to nucleosomes via an arginine anchor.

DNA连接酶3α的锌指通过精氨酸锚定与核小体结合。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66320-8
Nagpal Ashna, Schaich Matthew A, Weaver Tyler M, Roginskaya Vera, Sallmyr Annahita, Leary Liam P, Freudenthal Bret D, Tomkinson Alan E, Van Houten Bennett
发表日期：2025
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Nucleosome unwrapping and PARP1 allostery drive affinities for chromatin and DNA breaks.

核小体解旋和 PARP1 变构作用驱动对染色质和 DNA 断裂的亲和力。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67071-2
Schaich Matthew A, Weaver Tyler M, Rakowski Jennifer A, Roginskaya Vera, Leary Liam P, Van den Berg Aafke A, Iwasa Janet H, Freudenthal Bret D, Van Houten Bennett
PARP
PARP1
发表日期：2025
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APE1 active site residue Asn174 stabilizes the AP site and is essential for catalysis

APE1活性位点残基Asn174稳定AP位点，对催化至关重要。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110655
DeHart, Kaitlin M; Hoitsma, Nicole M; Thompson, Spencer H; Borin, Veniamin A; Agarwal, Pratul K; Freudenthal, Bret D
发表日期：2025
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Nucleosome unwrapping and PARP1 allostery drive affinities for chromatin and DNA breaks

核小体解旋和PARP1变构作用驱动对染色质和DNA断裂的亲和力

期刊:
影响因子:
doi:10.1101/2025.08.29.673134
Schaich, Matthew A; Weaver, Tyler M; Rakowski, Jennifer A; Roginskaya, Vera; Leary, Liam P; van den Berg, Aafke A; Iwasa, Janet H; Freudenthal, Bret D; Van Houten, Bennett
PARP1
PARP
发表日期：2025
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APE1 active site residue Asn174 stabilizes the AP-site and is essential for catalysis

APE1活性位点残基Asn174稳定AP位点，对催化至关重要。

期刊:
影响因子:
doi:10.1101/2025.01.14.633034
DeHart, Kaitlin M; Hoitsma, Nicole M; Thompson, Spencer H; Borin, Veniamin A; Agarwal, Pratul K; Freudenthal, Bret D
发表日期：2025
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Human ribomes reveal DNA-embedded ribonucleotides as a new type of epigenetic mark

人类核糖体组揭示了DNA嵌入的核糖核苷酸是一种新型的表观遗传标记。

期刊:
影响因子:
doi:10.1101/2025.06.27.661996
Kundnani, Deepali L; Yang, Taehwan; Channagiri, Tejasvi; Xu, Penghao; Lee, Yeunsoo; Sun, Mo; Martinez-Figueroa, Francisco; Randhawa, Supreet; Gogate, Ashlesha; Jeon, Youngkyu; Marsili, Stefania; Newnam, Gary; Lu, Yilin; Park, Vivian S; Tao, Sijia; Ling, Justin A; Schinazi, Raymond F; Pursell, Zachary F; Mohammed, Abdulmelik; Opresko, Patricia L; Freudenthal, Bret D; Kim, Baek; Yi, Soojin V; Jonoska, Nataša; Storici, Francesca
Human
表观遗传
发表日期：2025
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Structure, dynamics, and processing of 8oxoG:A in the nucleosome

核小体中8-氧鸟嘌呤的结构、动力学和加工

期刊:
影响因子:
doi:10.1101/2025.09.02.673820
Vito, Abigayle F; Ling, Justin A; Ferrara, Julia C; Jacques, Caleb S; Gillet, Natacha; Gonzalez-Aleman, Roy; Qiu, Yuya; Hashemian, Mohammad; Trasvina-Arenas, Carlos H; David, Sheila S; Delaney, Sarah; Bignon, Emmanuelle; Freudenthal, Bret D
发表日期：2025
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Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β

人DNA聚合酶β对Fapy•dG复制的生化和结构表征

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkae277
Gao, Shijun; Oden, Peyton N; Ryan, Benjamin J; Yang, Haozhe; Freudenthal, Bret D; Greenberg, Marc M
Human
发表日期：2024
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