日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.

通过合成剂量致死性鉴定 PLK1 过表达癌症的可靶向脆弱性

Cunningham Chelsea E, Vizeacoumar Frederick S, Zhang Yue, Kyrylenko Liliia, Both Simon, Maranda Vincent, Dong He, Price Jared D W, Gao Peng, Wagner Konrad, Wu Yingwen, Lazell-Wright Mary, Ganapathysamy Ashtalakshmi, Hari Rithik, Bhanumathy Kalpana K, Denomy Connor, Saxena Anjali, Vizeacoumar Jeff P, Morales Alain Morejon, Khan Faizaan, Mosley Shayla, Chen Angie, Katrii Tetiana, Zoller Ben G E, Rajamanickam Karthic, Walke Prachi, Gong Lihui, Patel Hardikkumar, Elhasasna Hussain, Dahiya Renuka, Abuhussein Omar, Dmitriev Anton, Freywald Tanya, Munhoz Erika Prando, Ruppin Eytan, Lee Joo Sang, Rox Katharina, Koebel Martin, Hopkins Laura, Lee Cheng Han, Yadav Sunil, Gasparoni Gilles, Walter Jörn, Krishnan Anand, Datla Raju, Toosi Behzad, Baker Kristi, Meens Jalna, Cescon David W, Ailles Laurie, Leary Scot C, Wu Yuliang, Empting Martin, Kiemer Alexandra K, Freywald Andrew, Vizeacoumar Franco J

A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer

Neurog2在MYCN驱动的前列腺癌神经内分泌可塑性中的新作用

Walke, Prachi; Price, Jared D W; Vizeacoumar, Frederick S; Joseph, Nickson; Maranda, Vincent; Chowdhury, Bari; Patel, Jay; Zhang, Yue; Dong, He; New, Lara; Ganapathysamy, Ashtalakshmi; Gong, Li Hui; Lazell-Wright, Mary; Elhasasna, Hussain; Bhanumathy, Kalpana K; Wu, Yuliang; Wang, Yuzhuo; Freywald, Andrew; Krishnan, Anand; Vizeacoumar, Franco J

EGFR Phosphorylates and Associates with EFNB1 to Regulate Cell Adhesion to Fibronectin.

EGFR 磷酸化并与 EFNB1 结合,从而调节细胞与纤连蛋白的粘附

Osornio-Hernández Ana I, Chartier François J M, Schuehle Tim L, Banerjee Sara L, Elowe Sabine, Laprise Patrick, Freywald Andrew, Laurin Mélanie, Bisson Nicolas

The DRP1 receptor FIS1 is critical to the expansion of triple-negative breast cancer tumor-initiating cells

DRP1受体FIS1对于三阴性乳腺癌肿瘤起始细胞的扩增至关重要。

Tetiana Katrii ,Tanya Freywald ,Malkon G Estrada ,Amr El Zawily ,Behzad Toosi ,Frederick S Vizeacoumar ,Franco J Vizeacoumar ,Andrew Freywald ,Scot C Leary #

MEMO1 binds iron and modulates iron homeostasis in cancer cells

MEMO1 结合铁并调节癌细胞中的铁稳态

Natalia Dolgova #, Eva-Maria E Uhlemann #, Michal T Boniecki #, Frederick S Vizeacoumar #, Anjuman Ara, Paria Nouri, Martina Ralle, Marco Tonelli, Syed A Abbas, Jaala Patry, Hussain Elhasasna, Andrew Freywald, Franco J Vizeacoumar, Oleg Y Dmitriev

Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model

利用基于图的无监督学习模型系统地比较 CRISPR 和 shRNA 筛选方法以识别必需基因

Ding, Yulian; Denomy, Connor; Freywald, Andrew; Pan, Yi; Vizeacoumar, Franco J; Vizeacoumar, Frederick S; Wu, Fang-Xiang

Cancer Cell's Achilles Heels: Considerations for Design of Anti-Cancer Drug Combinations

癌细胞的阿喀琉斯之踵:抗癌药物组合设计中的考量因素

Gahramanov, Valid; Vizeacoumar, Frederick S; Morales, Alain Morejon; Bonham, Keith; Sakharkar, Meena K; Kumar, Santosh; Vizeacoumar, Franco J; Freywald, Andrew; Sherman, Michael Y

Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment

乳腺肿瘤转移及其微环境:肿瘤的生长和治疗靶向都需要种子和土壤

Bonni, Shirin; Brindley, David N; Chamberlain, M Dean; Daneshvar-Baghbadorani, Nima; Freywald, Andrew; Hemmings, Denise G; Hombach-Klonisch, Sabine; Klonisch, Thomas; Raouf, Afshin; Shemanko, Carrie Simone; Topolnitska, Diana; Visser, Kaitlyn; Vizeacoumar, Franco J; Wang, Edwin; Gibson, Spencer B

Survey of NF1 inactivation by surrogate immunohistochemistry in ovarian carcinomas

通过替代免疫组织化学方法调查卵巢癌中的 NF1 失活

Martin Köbel, Rui Zhe Yang, Eun Young Kang, Zainab Al-Shamma, Linda S Cook, Mary Kinloch, Mark S Carey, Laura Hopkins, Gregg S Nelson, Kirk J McManus, Frederick S Vizeacoumar, Franco J Vizeacoumar, Andrew Freywald, YangXin Fu, David E Reuss, Cheng-Han Lee

A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers

药物再利用筛选发现磷酸氟达拉滨是治疗N-MYC过表达神经内分泌前列腺癌的潜在治疗药物

Hussain Elhasasna ,Raymond Khan ,Kalpana K Bhanumathy ,Frederick S Vizeacoumar ,Prachi Walke ,Maricris Bautista ,Dinesh K Dahiya ,Vincent Maranda ,Hardikkumar Patel ,Amrutha Balagopal ,Nezeka Alli ,Anand Krishnan ,Andrew Freywald ,Franco J Vizeacoumar