Fricker Lloyd D相关文献与解析，生知库 | 链接生命科学的每一步

ProSAAS neuropeptides and receptors GPR171 and GPR83: Potential therapeutic applications for pain, anxiety, and body weight regulation

ProSAAS神经肽及其受体GPR171和GPR83：在疼痛、焦虑和体重调节方面的潜在治疗应用

期刊:Journal of Pharmacology and Experimental Therapeutics

影响因子:3.8

doi:10.1016/j.jpet.2025.103599

Fricker, Lloyd D; Fakira, Amanda K; Bobeck, Erin N; Raddatz, Megan; Kim, Kelly; DeSchepper, Kayla D; Morgan, Daniel J

信号转导

发表日期：2025

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Ketamine and Major Ketamine Metabolites Function as Allosteric Modulators of Opioid Receptors.

氯胺酮及其主要代谢物作为阿片受体的变构调节剂发挥作用

期刊:Molecular Pharmacology

影响因子:3

doi:10.1124/molpharm.124.000947

Gomes Ivone, Gupta Achla, Margolis Elyssa B, Fricker Lloyd D, Devi Lakshmi A

代谢

发表日期：2024

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Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides

携带 CPE 无效突变的杂合子小鼠表现出羧肽酶 e mRNA 表达和酶活性降低，但生理、行为和神经肽水平正常。

期刊:Brain Research

影响因子:2.6

doi:10.1016/j.brainres.2022.147951

Fricker, Lloyd D; Lemos Duarte, Mariana; Jeltyi, Andrei; Lueptow, Lindsay; Fakira, Amanda K; Tashima, Alexandre K; Hochgeschwender, Ute; Wetsel, William C; Devi, Lakshmi A

发表日期：2022

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Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary

小鼠脑和垂体中基因定义的细胞类型的神经肽组学分析

期刊:Cell Chemical Biology

影响因子:7.2

doi:10.1016/j.chembiol.2020.11.003

Fricker, Lloyd D; Tashima, Alexandre K; Fakira, Amanda K; Hochgeschwender, Ute; Wetsel, William C; Devi, Lakshmi A

Obesity, POMC, and POMC-processing Enzymes: Surprising Results From Animal Models

肥胖、POMC 和 POMC 加工酶：动物模型研究的惊人结果

期刊:Endocrinology

影响因子:3.3

doi:10.1210/endocr/bqab155

Lindberg, Iris; Fricker, Lloyd D

Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain

人羧肽酶Z的底物特异性和结构建模：一种具有卷曲样结构域的独特蛋白酶

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms21228687

Garcia-Pardo, Javier; Tanco, Sebastian; Garcia-Guerrero, Maria C; Dasgupta, Sayani; Avilés, Francesc Xavier; Lorenzo, Julia; Fricker, Lloyd D

Human

发表日期：2020

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Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions

阿片肽研究五十年：现状与未解之谜

期刊:Molecular Pharmacology

影响因子:3

doi:10.1124/mol.120.119388

Fricker, Lloyd D; Margolis, Elyssa B; Gomes, Ivone; Devi, Lakshmi A

发表日期：2020

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Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells

蛋白质变性和酶抑制剂对人胚肾细胞中蛋白酶体介导的肽类生成的影响

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom9060207

Dasgupta, Sayani; Fishman, Michael A; Castro, Leandro M; Tashima, Alexandre K; Ferro, Emer S; Fricker, Lloyd D

Identification and characterization of RSIY-11, a novel seminal peptide derived from semenogelin-1, which acts as a neutral endopeptidase inhibitor modulating sperm motility.

对 RSIY-11 进行了鉴定和表征，RSIY-11 是一种源自精液凝集素-1 的新型精液肽，它是一种中性内肽酶抑制剂，可调节精子活力

期刊:Journal of Assisted Reproduction and Genetics

影响因子:2.7

doi:10.1007/s10815-019-01524-8

Fritz Rani, Mukherjee Amarnath, Zaghi Sahar, Agalliu Ilir, Jindal Sangita, Tashima Alexandre K, Fricker Lloyd D, Davies Kelvin P

其它

发表日期：2019

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Antidepressants and the endogenous opioid system

抗抑郁药与内源性阿片系统

ProSAAS neuropeptides and receptors GPR171 and GPR83: Potential therapeutic applications for pain, anxiety, and body weight regulation

ProSAAS神经肽及其受体GPR171和GPR83：在疼痛、焦虑和体重调节方面的潜在治疗应用

Ketamine and Major Ketamine Metabolites Function as Allosteric Modulators of Opioid Receptors.

氯胺酮及其主要代谢物作为阿片受体的变构调节剂发挥作用

Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides

携带 CPE 无效突变的杂合子小鼠表现出羧肽酶 e mRNA 表达和酶活性降低，但生理、行为和神经肽水平正常。

Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary

小鼠脑和垂体中基因定义的细胞类型的神经肽组学分析

Obesity, POMC, and POMC-processing Enzymes: Surprising Results From Animal Models

肥胖、POMC 和 POMC 加工酶：动物模型研究的惊人结果

Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain

人羧肽酶Z的底物特异性和结构建模：一种具有卷曲样结构域的独特蛋白酶

Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions

阿片肽研究五十年：现状与未解之谜

Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells

蛋白质变性和酶抑制剂对人胚肾细胞中蛋白酶体介导的肽类生成的影响

Identification and characterization of RSIY-11, a novel seminal peptide derived from semenogelin-1, which acts as a neutral endopeptidase inhibitor modulating sperm motility.

对 RSIY-11 进行了鉴定和表征，RSIY-11 是一种源自精液凝集素-1 的新型精液肽，它是一种中性内肽酶抑制剂，可调节精子活力