日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Estimation of Absolute Binding Free Energies for Drugs That Bind Multiple Proteins

估算与多种蛋白质结合的药物的绝对结合自由能

Lindahl, Erik; Friedman, Ran

A computational dynamic model of combination treatment for type II inhibitors with asciminib

针对 II 型抑制剂与 asciminib 联合治疗的计算动态模型

Sheehan, J Roadnight; de Wijn, Astrid S; Friedman, Ran

Unveiling the Catalytic Mechanism of Abl1 Kinase: A Single-Magnesium Ion Pathway for Phosphoryl Transfer

揭示Abl1激酶的催化机制:单镁离子途径介导的磷酸转移

Bjelic, Sinisa; Maganhi, Stella Hernandez; Friedman, Ran

Beyond IC50-A computational dynamic model of drug resistance in enzyme inhibition treatment

超越IC50——酶抑制治疗中药物耐药性的计算动态模型

Roadnight Sheehan, J; de Wijn, Astrid S; Freire, Thales Souza; Friedman, Ran

Exploring the Impact of Protein Chain Selection in Binding Energy Calculations with DFT

利用密度泛函理论探讨蛋白质链选择对结合能计算的影响

Lindahl, Erik; Friedman, Ran

Estimating the Gibbs Hydration Energies of Actinium and Trans-Plutonium Actinides

估算锕系和超钚系锕系元素的吉布斯水合能

Friedman, Ran

Activation of Abl1 Kinase Explored Using Well-Tempered Metadynamics Simulations on an Essential Dynamics Sampled Path

利用良好调控的元动力学模拟在基本动力学采样路径上探索 Abl1 激酶的激活

Oruganti, Baswanth; Friedman, Ran

The effects of combination treatments on drug resistance in chronic myeloid leukaemia: an evaluation of the tyrosine kinase inhibitors axitinib and asciminib

联合治疗对慢性粒细胞白血病耐药性的影响:酪氨酸激酶抑制剂阿昔替尼和阿西米尼的评价

G Lindström, H Jonathan; Friedman, Ran

Inferring time-dependent population growth rates in cell cultures undergoing adaptation

推断适应性细胞培养物中随时间变化的人口增长率

Lindström, H Jonathan G; Friedman, Ran

Reverse engineering directed gene regulatory networks from transcriptomics and proteomics data of biomining bacterial communities with approximate Bayesian computation and steady-state signalling simulations

利用近似贝叶斯计算和稳态信号模拟,从生物采矿细菌群落的转录组学和蛋白质组学数据中逆向工程定向基因调控网络

Buetti-Dinh, Antoine; Herold, Malte; Christel, Stephan; El Hajjami, Mohamed; Delogu, Francesco; Ilie, Olga; Bellenberg, Sören; Wilmes, Paul; Poetsch, Ansgar; Sand, Wolfgang; Vera, Mario; Pivkin, Igor V; Friedman, Ran; Dopson, Mark