Frit相关文献与解析，生知库 | 链接生命科学的每一步

Hall, Chloe; Frit, Philippe; Kefala-Stavridi, Antonia; Pelletier, Amandine; Hardwick, Steven W; Amin, Himani; Bilyard, Matthew K; Maia De Oliviera, Taiana; Tariq, Ammarah; Zahid, Sayma; Chirgadze, Dimitri Y; Balasubramanian, Shankar; Meek, Katheryn; Ropars, Virginie; Charbonnier, Jean-Baptiste; Modesti, Mauro; Calsou, Patrick; Britton, Sébastien; Blundell, Tom L; Schalch, Thomas; Chaplin, Amanda K

发表日期：2025

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Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ.

对Ku70/80和Pol X家族聚合酶在NHEJ中的相互作用的结构和功能见解

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-59133-2

Frit Philippe, Amin Himani, Zahid Sayma, Barboule Nadia, Hall Chloe, Matharu Gurdip, Hardwick Steven W, Chauvat Jeanne, Britton SÃ©bastien, Chirgadze Dima Y, Ropars Virginie, Charbonnier Jean-Baptiste, Calsou Patrick, Chaplin Amanda K

免疫/内分泌

发表日期：2025

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Synthesis, characterization, computational and biological evaluation of pyrazole hydrazones as promising anti-inflammatory agents

吡唑腙类化合物的合成、表征、计算和生物学评价及其作为潜在抗炎药物的价值

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-26088-9

Deshmukh, Hemant S; Adole, Vishnu A; Frit, A Alfind Paul; Mali, Suraj N; Yasin, Haya Khader Ahmad; Patil, Bhausaheb N; Janani, S; Jagdale, Bapu S

发表日期：2025

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Retraction notice to "Heat shock factor 5 establishes the male germ-line meiotic sex chromosome inactivation through regulation of Smarca4" [Heliyon 9 (2023) e15194]

撤稿声明：“热休克因子 5 通过调控 Smarca4 建立雄性生殖细胞减数分裂性染色体失活”[Heliyon 9 (2023) e15194]

期刊:Heliyon

影响因子:3.6

doi:10.1016/j.heliyon.2025.e43282

Barutc, A Rasim; Frit, Andrew J; McCor, Rachel P; Nick, Jeffrey A; Asla, Muhammad

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction

肌醇六磷酸通过稳定 Ku-XLF 相互作用刺激 NHEJ 的结构和功能基础

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkad863

Antonia Kefala Stavridi, Amandine Gontier, Vincent Morin, Philippe Frit, Virginie Ropars, Nadia Barboule, Carine Racca, Sagun Jonchhe, Michael J Morten, Jessica Andreani, Alexey Rak, Pierre Legrand, Alexa Bourand-Plantefol, Steven W Hardwick, Dimitri Y Chirgadze, Paul Davey, Taiana Maia De Oliveira,

PAXX binding to the NHEJ machinery explains functional redundancy with XLF

PAXX 与 NHEJ 机制的结合解释了 XLF 的功能冗余

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adg2834

Murielle Seif-El-Dahan, Antonia Kefala-Stavridi, Philippe Frit, Steven W Hardwick, Dima Y Chirgadze, Taiana Maia De Oliviera, Jessica Andreani, Sébastien Britton, Nadia Barboule, Madeleine Bossaert, Arun Prasad Pandurangan, Katheryn Meek, Tom L Blundell, Virginie Ropars, Patrick Calsou, Jean-Baptist

Heat shock factor 5 establishes the male germ-line meiotic sex chromosome inactivation through regulation of Smarca4

热休克因子5通过调控Smarca4，建立雄性生殖细胞减数分裂性染色体的失活。

期刊:Heliyon

影响因子:3.6

doi:10.1016/j.heliyon.2023.e15194

Barutc, A Rasim; Frit, Andrew J; McCor, Rachel P; Nick, Jeffrey A; Asla, Muhammad

Arginyl-tRNA-protein transferase 1 (ATE1) promotes melanoma cell growth and migration

精氨酰-tRNA-蛋白转移酶1（ATE1）促进黑色素瘤细胞生长和迁移

期刊:FEBS Letters

影响因子:3

doi:10.1002/1873-3468.14376

Ikrame Lazar, Bertrand Fabre, Yongmei Feng, Ali Khateb, Philippe Frit, Anna Kashina, Tongwu Zhang, Emily Avitan-Hersh, Hyungsoo Kim, Kevin Brown, Ivan Topisirovic, Ze'ev A Ronai

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks

ATM 拮抗 NHEJ 蛋白组装和 DNA 末端突触在单端 DNA 双链断裂处

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkaa723

Sébastien Britton, Pauline Chanut, Christine Delteil, Nadia Barboule, Philippe Frit, Patrick Calsou

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

XLF 和 APLF 在两个远程位点结合 Ku80，以确保通过非同源末端连接进行 DNA 修复

期刊:Nature Structural & Molecular Biology

影响因子:12.5

doi:10.1038/s41594-018-0133-6

Clement Nemoz, Virginie Ropars, Philippe Frit, Amandine Gontier, Pascal Drevet, Jinchao Yu, Raphaël Guerois, Aurelien Pitois, Audrey Comte, Christine Delteil, Nadia Barboule, Pierre Legrand, Sonia Baconnais, Yandong Yin, Satish Tadi, Emeline Barbet-Massin, Imre Berger, Eric Le Cam, Mauro Modesti, El

信号转导

发表日期：2018

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Cryo-EM structures of NHEJ assemblies with nucleosomes

核小体参与的NHEJ组装体的冷冻电镜结构

Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ.

对Ku70/80和Pol X家族聚合酶在NHEJ中的相互作用的结构和功能见解

Synthesis, characterization, computational and biological evaluation of pyrazole hydrazones as promising anti-inflammatory agents

吡唑腙类化合物的合成、表征、计算和生物学评价及其作为潜在抗炎药物的价值

Retraction notice to "Heat shock factor 5 establishes the male germ-line meiotic sex chromosome inactivation through regulation of Smarca4" [Heliyon 9 (2023) e15194]

撤稿声明：“热休克因子 5 通过调控 Smarca4 建立雄性生殖细胞减数分裂性染色体失活”[Heliyon 9 (2023) e15194]

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction

肌醇六磷酸通过稳定 Ku-XLF 相互作用刺激 NHEJ 的结构和功能基础

PAXX binding to the NHEJ machinery explains functional redundancy with XLF

PAXX 与 NHEJ 机制的结合解释了 XLF 的功能冗余

Heat shock factor 5 establishes the male germ-line meiotic sex chromosome inactivation through regulation of Smarca4

热休克因子5通过调控Smarca4，建立雄性生殖细胞减数分裂性染色体的失活。

Arginyl-tRNA-protein transferase 1 (ATE1) promotes melanoma cell growth and migration

精氨酰-tRNA-蛋白转移酶1（ATE1）促进黑色素瘤细胞生长和迁移

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks

ATM 拮抗 NHEJ 蛋白组装和 DNA 末端突触在单端 DNA 双链断裂处

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

XLF 和 APLF 在两个远程位点结合 Ku80，以确保通过非同源末端连接进行 DNA 修复