日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape

聚对苯二甲酸乙二醇酯降解角质酶的祖先重建揭示了一个崎岖且尚未探索的序列适应性图景

Vongsouthi, Vanessa; Georgelin, Rosemary; Matthews, Dana S; Saunders, Jake; Lee, Brendon M; Ton, Jennifer; Damry, Adam M; Frkic, Rebecca L; Spence, Matthew A; Jackson, Colin J

Expanding the biocatalytic and oxidative landscape of the old yellow enzyme family

拓展古老黄酶家族的生物催化和氧化作用范围

White, David W; Frkic, Rebecca L; Iamurri, Samantha; Keshavarz-Joud, Parisa; Blue, Tamra; Jackson, Colin J; Copp, Janine; Lutz, Stefan

Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC

分离、鉴定和表征孔雀石绿解毒细菌菌株太平洋芽孢杆菌ROC1及其偶氮还原酶AzrC

Bibi, Shanza; Breeze, Callum W; Jadoon, Vusqa; Fareed, Anum; Syed, Alina; Frkic, Rebecca L; Zaffar, Habiba; Ali, Muhammad; Zeb, Iftikhar; Jackson, Colin J; Naqvi, Tatheer Alam

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

一种能降解有机磷酸酯增塑剂的耐热细菌金属水解酶

Ji, Dawei; Frkic, Rebecca L; Delyami, Javad; Larsen, Joachim S; Spence, Matthew A; Jackson, Colin J

Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase

铕(III)和钆(III)在模型金属酶磷酸三酯酶活性位点的单核结合和催化活性

Breeze, Callum W; Nakano, Yuji; Campbell, Eleanor C; Frkic, Rebecca L; Lupton, David W; Jackson, Colin J

Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction

利用腈-氨基硫醇点击反应进行细胞内蛋白质大环化的氰基吡啶丙氨酸的基因编码

Abdelkader, Elwy H; Qianzhu, Haocheng; George, Josemon; Frkic, Rebecca L; Jackson, Colin J; Nitsche, Christoph; Otting, Gottfried; Huber, Thomas

Antiviral cyclic peptides targeting the main protease of SARS-CoV-2

针对 SARS-CoV-2 主要蛋白酶的抗病毒环肽

Jason Johansen-Leete, Sven Ullrich, Sarah E Fry, Rebecca Frkic, Max J Bedding, Anupriya Aggarwal, Anneliese S Ashhurst, Kasuni B Ekanayake, Mithun C Mahawaththa, Vishnu M Sasi, Stephanie Luedtke, Daniel J Ford, Anthony J O'Donoghue, Toby Passioura, Mark Larance, Gottfried Otting, Stuart Turville, Co

The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes

抑制PPARγ磷酸化治疗2型糖尿病的治疗潜力

Frkic, Rebecca L; Richter, Katharina; Bruning, John B

PPARγ in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix

PPARγ 与拮抗剂和反向激动剂的复合物:激活螺旋的翻滚和捕获机制

Frkic, Rebecca L; Marshall, Andrew C; Blayo, Anne-Laure; Pukala, Tara L; Kamenecka, Theodore M; Griffin, Patrick R; Bruning, John B

Structural and Dynamic Elucidation of a Non-acid PPARγ Partial Agonist: SR1988

非酸性PPARγ部分激动剂SR1988的结构和动力学解析

Frkic, Rebecca L; Chua, Benjamin S; Shin, Youseung; Pascal, Bruce D; Novick, Scott J; Kamenecka, Theodore M; Griffin, Patrick R; Bruning, John B