Frlan相关文献与解析，生知库 | 链接生命科学的每一步

Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis

发现针对细菌肽聚糖生物合成的 D-Ala:D-Ala 连接酶的片段命中化合物

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry

影响因子:5.6

doi:10.1080/14756366.2022.2149745

Matic Proj, Martina Hrast, Gregor Bajc, Rok Frlan, Anže Meden, Matej Butala, Stanislav Gobec

微生物学

发表日期：2023

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Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (-)-epicatechin

Mur 连接酶 F 是黄酮类化合物槲皮素、杨梅素和 (-)-表儿茶素的新靶标

期刊:Journal of Computer-Aided Molecular Design

影响因子:3

doi:10.1007/s10822-023-00535-z

Martina Hrast Rambaher, Irena Zdovc, Nina Kočevar Glavač, Stanislav Gobec, Rok Frlan

信号转导

发表日期：2023

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An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway

细菌莽草酸途径酶的进化保守性和成药性分析

期刊:Antibiotics-Basel

影响因子:4.6

doi:10.3390/antibiotics11050675

Essential Oil and Hydrosol Composition of Immortelle (Helichrysumitalicum)

蜡菊（Helichrysumitalicum）精油和纯露成分

期刊:Plants-Basel

影响因子:4.1

doi:10.3390/plants11192573

Kunc, Nina; Frlan, Antonela; Baričevič, Dea; Kočevar Glavač, Nina; Kokalj Ladan, Meta

发表日期：2022

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Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?

在基于片段的药物发现活动中，片段大小的噻唑类化合物是敌是友？

期刊:ACS Medicinal Chemistry Letters

影响因子:4

doi:10.1021/acsmedchemlett.2c00429

Proj, Matic; Hrast, Martina; Knez, Damijan; Bozovičar, Krištof; Grabrijan, Katarina; Meden, Anže; Gobec, Stanislav; Frlan, Rok

发表日期：2022

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Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs

Lepechinia meyenii二萜及其合成类似物对大肠杆菌和金黄色葡萄球菌MurA酶的抑制作用

期刊:Antibiotics-Basel

影响因子:

doi:10.3390/antibiotics10121535

Macarena Funes Chabán, Martina Hrast, Rok Frlan, Dafni G Graikioti, Constantinos M Athanassopoulos, María Cecilia Carpinella

微生物学

发表日期：2021

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Efficient and Straightforward Syntheses of Two United States Pharmacopeia Sitagliptin Impurities: 3-Desamino-2,3-dehydrositagliptin and 3-Desamino-3,4-dehydrositagliptin

高效简便地合成两种美国药典收录的西格列汀杂质：3-脱氨基-2,3-脱氢西格列汀和3-脱氨基-3,4-脱氢西格列汀

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.9b04393

Sova, Matej; Frlan, Rok; Gobec, Stanislav; Časar, Zdenko

发表日期：2020

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Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening

通过基于结构的虚拟筛选鉴定新型结构类别的 HV1 抑制剂

Navigating the Chemical Space of ENR Inhibitors: A Comprehensive Analysis

ENR抑制剂化学空间探索：一项综合分析

Using Subcritical Water to Obtain Polyphenol-Rich Extracts with Antimicrobial Properties

利用亚临界水提取具有抗菌性能的富含多酚的提取物

Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis

发现针对细菌肽聚糖生物合成的 D-Ala:D-Ala 连接酶的片段命中化合物

Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (-)-epicatechin

Mur 连接酶 F 是黄酮类化合物槲皮素、杨梅素和 (-)-表儿茶素的新靶标

An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway

细菌莽草酸途径酶的进化保守性和成药性分析

Essential Oil and Hydrosol Composition of Immortelle (Helichrysumitalicum)

蜡菊（Helichrysumitalicum）精油和纯露成分

Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?

在基于片段的药物发现活动中，片段大小的噻唑类化合物是敌是友？

Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs

Lepechinia meyenii二萜及其合成类似物对大肠杆菌和金黄色葡萄球菌MurA酶的抑制作用

Efficient and Straightforward Syntheses of Two United States Pharmacopeia Sitagliptin Impurities: 3-Desamino-2,3-dehydrositagliptin and 3-Desamino-3,4-dehydrositagliptin

高效简便地合成两种美国药典收录的西格列汀杂质：3-脱氨基-2,3-脱氢西格列汀和3-脱氨基-3,4-脱氢西格列汀