日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Fast and slow strains of misfolded mutant superoxide dismutase 1 in familial amyotrophic lateral sclerosis

家族性肌萎缩侧索硬化症中错误折叠突变超氧化物歧化酶 1 的快慢两种菌株

Xu, Guilian; Dillon, Kristy; Lopez, Amanda; Brkic, Selma; Fromholt, Susan; Ostrow, Lyle W; Glass, Jonathan D; Chakrabarty, Paramita; Ayers, Jacob I; Borchelt, David R

Efficient induction of motor neuron disease in transgenic G93A SOD1 mice by prion-like seeding

通过朊病毒样播种在转基因G93A SOD1小鼠中高效诱导运动神经元疾病

Xu, Guilian; Lopez, Amanda; Brkic, Selma; Fromholt, Susan; Chakrabarty, Paramita; Borchelt, David R

Correction: Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model

更正:α-突触核蛋白和Aβ的协同作用加剧了新型朊病毒型小鼠模型中的合并症

Lloyd, Grace M; Dhillon, Jess-Karan S; Gorion, Kimberly-Marie M; Riffe, Cara; Fromholt, Susan E; Xia, Yuxing; Giasson, Benoit I; Borchelt, David R

Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice

多种因素影响SOD1转基因小鼠ALS朊病毒样传播的潜伏期

Ayers, Jacob I; Xu, Guilian; Lu, Qing; Dillon, Kristy; Fromholt, Susan; Borchelt, David R

Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts

将来自不同人类和小鼠来源的可溶性脑匀浆注射到新生小鼠体内后,会优先诱导弥漫性Aβ斑块病变的发生。

Moore, Brenda D; Levites, Yona; Xu, Guilian; Hampton, Hailey; Adamo, Munir F; Croft, Cara L; Futch, Hunter S; Moran, Corey; Fromholt, Susan; Janus, Christopher; Prokop, Stefan; Dickson, Dennis; Lewis, Jada; Giasson, Benoit I; Golde, Todd E; Borchelt, David R

Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease

模拟错误折叠的Aβ构象异构体之间的竞争,这些构象异构体在阿尔茨海默病中产生不同类型的淀粉样蛋白病理

Xu, Guilian; Fromholt, Susan; Borchelt, David R

MBRS-06. Gli3 INDUCES NEURONAL DIFFERENTIATION IN WNT- AND SHH- ACTIVATED MEDULLOBLASTOMA

MBRS-06. Gli3诱导WNT和SHH激活的髓母细胞瘤发生神经元分化

Pan, Baohan; Fromholt, Susan E; Hess, Ellen J; Crawford, Thomas O; Griffin, John W; Sheikh, Kazim A; Schnaar, Ronald L; Natsumeda, Manabu; Miyahara, Hiroaki; Yoshimura, Junichi; Tsukamoto, Yoshihiro; Oishi, Makoto; Wataya, Takafumi; Eberhart, Charles; Kakita, Akiyoshi; Fujii, Yukihiko

Retraction Note: Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype

撤稿声明:过表达与肌萎缩侧索硬化症相关的蛋白Matrin 3的转基因小鼠会发展出严重的肌肉表型

Moloney, Christina; Rayaprolu, Sruti; Howard, John; Fromholt, Susan; Brown, Hilda; Collins, Matt; Cabrera, Mariela; Duffy, Colin; Siemienski, Zoe; Miller, Dave; Swanson, Maurice S; Notterpek, Lucia; Borchelt, David R; Lewis, Jada

Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

突变型SOD1错误折叠和运动神经元疾病的朊病毒样传播沿神经解剖通路扩散

Ayers, Jacob I; Fromholt, Susan E; O'Neal, Veronica M; Diamond, Jeffrey H; Borchelt, David R

Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS

可传播的错误折叠SOD1的不同构象将人类SOD1-FALS与其他类型的家族性和散发性ALS区分开来。

Ayers, Jacob I; Diamond, Jeffrey; Sari, Adriana; Fromholt, Susan; Galaleldeen, Ahmad; Ostrow, Lyle W; Glass, Jonathan D; Hart, P John; Borchelt, David R