Passaging Human Tauopathy Patient Samples in Cells Generates Heterogeneous Fibrils with a Subpopulation Adopting Disease Folds
在细胞中传代培养人类tau蛋白病患者样本会产生异质性纤维,其中一部分纤维会呈现疾病折叠。
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doi:10.1101/2023.07.19.549721
Zeng, Zhikai; Tsay, Karen; Vijayan, Vishnu; Frost, Matthew P; Prakash, Shikhar; Quddus, Athena; Albert, Alexa; Vigers, Michael; Srivastava, Madhur; Woerman, Amanda L; Han, Songi