日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic association analysis of 77,539 genomes reveals rare disease etiologies

77,539 个基因组的遗传关联分析揭示了罕见疾病的病因

Daniel Greene; Genomics England Research Consortium; Daniela Pirri, Karen Frudd, Ege Sackey, Mohammed Al-Owain, Arnaud P J Giese, Khushnooda Ramzan, Sehar Riaz, Itaru Yamanaka, Nele Boeckx, Chantal Thys, Bruce D Gelb, Paul Brennan, Verity Hartill, Julie Harvengt, Tomoki Kosho, Sahar Mansour, Mitsuo

Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier

甲基苯丙胺增强治疗药物通过啮齿动物血脑屏障的洞穴运输

Jui-Hsien Chang, Chris Greene, Karen Frudd, Leonardo Araujo Dos Santos, Clare Futter, Benjamin J Nichols, Matthew Campbell, Patric Turowski

Multicenter Evaluation of Diagnostic Circulating Biomarkers to Detect Sight-Threatening Diabetic Retinopathy

多中心评估诊断性循环生物标志物在检测威胁视力的糖尿病视网膜病变中的应用

Gurudas, Sarega; Frudd, Karen; Maheshwari, Jayapal Jeya; Revathy, Yeddula Rebecca; Sivaprasad, Sobha; Ramanathan, Shruthi Mahalakshmi; Pooleeswaran, Vignesh; Prevost, A Toby; Karatsai, Eleni; Halim, Sandra; Chandra, Shruti; Nderitu, Paul; Conroy, Dolores; Krishnakumar, Subramanian; Parameswaran, Sowmya; Dharmalingam, Kuppamuthu; Ramasamy, Kim; Raman, Rajiv; Jones, Colin; Eleftheriadis, Haralabos; Greenwood, John; Turowski, Patric

Diagnostic circulating biomarkers to detect vision-threatening diabetic retinopathy: Potential screening tool of the future?

利用循环生物标志物诊断威胁视力的糖尿病视网膜病变:未来潜在的筛查工具?

Frudd, Karen; Sivaprasad, Sobha; Raman, Rajiv; Krishnakumar, Subramanian; Revathy, Yeddula Rebecca; Turowski, Patric

CCL4 induces inflammatory signalling and barrier disruption in the neurovascular endothelium

CCL4诱导神经血管内皮细胞的炎症信号传导和屏障破坏。

Estevao, Carolina; Bowers, Chantelle E; Luo, Ding; Sarker, Mosharraf; Hoeh, Alexandra Eva; Frudd, Karen; Turowski, Patric; Greenwood, John

The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program

转录因子ERG调控与内皮细胞特异性基因表达程序相关的超级增强子

Kalna, Viktoria; Yang, Youwen; Peghaire, Claire R; Frudd, Karen; Hannah, Rebecca; Shah, Aarti V; Osuna Almagro, Lourdes; Boyle, Joseph J; Göttgens, Berthold; Ferrer, Jorge; Randi, Anna M; Birdsey, Graeme M

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy

Atg3和Atg7的氧化介导自噬的抑制

Frudd, Karen; Burgoyne, Thomas; Burgoyne, Joseph Robert

Sequential binding of ezrin and moesin to L-selectin regulates monocyte protrusive behaviour during transendothelial migration

埃兹蛋白和膜突蛋白与 L-选择素的顺序结合调节跨内皮迁移过程中单核细胞的突出行为

Angela Rey-Gallardo, Hannah Tomlins, Justin Joachim, Izajur Rahman, Phoebe Kitscha, Karen Frudd, Maddy Parsons, Aleksandar Ivetic

Endoplasmic reticulum (ER) stress and hypoxia response pathways interact to potentiate hypoxia-inducible factor 1 (HIF-1) transcriptional activity on targets like vascular endothelial growth factor (VEGF)

内质网 (ER) 应激和缺氧反应途径相互作用,增强缺氧诱导因子 1 (HIF-1) 对血管内皮生长因子 (VEGF) 等靶标的转录活性

Ethel R Pereira, Karen Frudd, Walid Awad, Linda M Hendershot