日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neo-Cysteine Molecular Glues for Targeting Mutated SMAD4 Protein

用于靶向突变SMAD4蛋白的新半胱氨酸分子胶

Kumari, Pooja; Oum, Yoon Hyeun; Miller, Eric J; Qui, Min; Du, Yuhong; Mou, Hongmei; Singh, Rakesh; Fu, Haian; Mo, Xiulei

Stalling the Enemy: Targeting Nsp13 for Next-Generation SARS-CoV-2 Antivirals

阻击敌人:以 Nsp13 为靶点开发下一代 SARS-CoV-2 抗病毒药物

Castro, Jose M; Slack, Ryan L; Ong, Yee T; Zhang, Huanchun; Gifford, Levi B; Courouble, Valentine V; Aiken, Riley M; Shankar, Vishal; O'Leary, Timothy R; Griffin, Patrick R; Lan, Shuiyun; Du, Yuhong; Fu, Haian; Sarafianos, Stefan G

Correction: LKB1 promotes cell survival by modulating TIF-IA-mediated pre-ribosomal RNA synthesis under uridine downregulated conditions

更正:在尿苷水平下调的情况下,LKB1通过调节TIF-IA介导的前体核糖体RNA合成来促进细胞存活。

Liu, Fakeng; Jin, Rui; Liu, Xiuju; Huang, Henry; Wilkinson, Scott C; Zhong, Diansheng; Khuri, Fadlo R; Fu, Haian; Marcus, Adam; He, Yulong; Zhou, Wei

Decoding the functional impact of the cancer genome through protein-protein interactions

通过蛋白质-蛋白质相互作用解码癌症基因组的功能影响

Fu, Haian; Mo, Xiulei; Ivanov, Andrey A

Integrated phenotypic and proteomic screening identifies top-tier Alzheimer's disease therapeutic targets

整合表型和蛋白质组学筛选鉴定出阿尔茨海默病的一流治疗靶点

Cary, Gregory A; Li, Qianjin; Wiley, Jesse C; Paisie, Carolyn A; Du, Yuhong; Zoeller, Elizabeth L; Duong, Duc; Fu, Haian; Seyfried, Nicholas T; Levey, Allan I; Betarbet, Ranjita; Carter, Gregory W

Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer.

靶向 MKK3/c-Myc 相互作用以克服 EGFR 突变肺癌中奥希替尼的获得性耐药性。

Chen Zhen, Vallega Karin A, Wang Dongsheng, Bildtsen Elsa, Fu Haian, Ramalingam Suresh S, Ivanov Andrey A, Sun Shi-Yong

Suppression of LKB1-mutant lung adenocarcinoma by natural killer cells from females.

女性自然杀伤细胞对LKB1突变型肺腺癌的抑制作用

Fan Yijian, Jin Rui, Monterroza Lenore, Liu Xiuju, Huang Chunzi, Marra Angelo, Mo Xiulei, Fu Haian, Gilbert-Ross Melissa, Marcus Adam I, Tirouvanziam Rabindra, Liu Yuan, Schneider Frank, Zhou Wei

Alexidine is a TAZ-specific small-molecule inhibitor that suppresses breast cancer invasion and metastasis.

Alexidine 是一种 TAZ 特异性小分子抑制剂,可抑制乳腺癌的侵袭和转移。

Ge Anni, Niu Lishui, Rubino Rachel, Seaman Kimberly, Song Xin, Hao Yawei, Klupt Kody, Iaboni Natasha, Jia Zongchao, You Lidan, Nicol Christopher J B, Fu Haian, Du Yuhong, Yang Xiaolong

High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma.

PER1 高表达与 STK11 突变和肺腺癌免疫治疗耐药的临床生物标志物相关

Parker Rebecca E, McSwain Leon, Zhou Wei, Marcus Adam I, Fu Haian, Ramalingam Suresh S, Zhang Shirley, Gilbert-Ross Melissa

Miniaturization of Human iPSC‐derived neuron long‐term culture into high‐throughput screening format for AD biology and therapeutics discovery

将人诱导多能干细胞衍生神经元长期培养微型化为高通量筛选模式,用于阿尔茨海默病生物学和治疗方法的发现

Cucinotta, Francis A; Eliedonna Cacao, Murat Alp; Du, Yuhong; Zhou, Ying; Qui, Min; Zoeller, Elizabeth L; Betarbet, Ranjita; Siciliano, Benjamin; Levey, Allan I; Fu, Haian; Wen, Zhexing