日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Zinc-limited Mycobacterium tuberculosis stimulate distinct responses in macrophages compared with standard zinc-replete bacteria

与锌充足的标准细菌相比,锌缺乏的结核分枝杆菌会刺激巨噬细胞产生不同的反应。

Endrei Marcantonio ,Allexa D Burger ,Kelly H Chang ,Fukun W Hoffmann ,Yuanyuan Fu ,Vedbar S Khadka ,Benoit J Smagghe ,Youping Deng ,Peter R Hoffmann ,Sladjana Prisic

Selenoprotein I is indispensable for ether lipid homeostasis and proper myelination

硒蛋白I对于醚脂稳态和正常的髓鞘形成至关重要。

Lance G A Nunes ,Chi Ma ,FuKun W Hoffmann ,Ashley E Shay ,Matthew W Pitts ,Peter R Hoffmann

Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells

脂多糖诱导的B细胞活化过程中硒蛋白I表达上调,促进脂质组学改变,并且是B细胞有效分化为分泌IgM的浆细胞所必需的。

Ma, Chi; Hoffmann, FuKun W; Shay, Ashley E; Koo, Imhoi; Green, Kathy A; Green, William R; Hoffmann, Peter R

Depletion of monocytic myeloid-derived suppressor cells in LP-BM5 murine retroviral infection has a positive impact on virus-induced host immunodeficiency

在LP-BM5小鼠逆转录病毒感染中,单核细胞来源的髓系抑制细胞的耗竭对病毒诱导的宿主免疫缺陷有积极影响。

Green, Kathy A; Ma, Chi; Hoffmann, Fukun W; Hoffmann, Peter R; Green, William R

T-cell activation decreases miRNA-15a/16 levels to promote MEK1-ERK1/2-Elk1 signaling and proliferative capacity

T细胞活化通过降低miRNA-15a/16水平来促进MEK1-ERK1/2-Elk1信号通路和增殖能力。

Frank Urena ,Chi Ma ,FuKun W Hoffmann ,Lance G A Nunes ,Johann Urschitz ,Stefan Moisyadi ,Vedbar S Khadka ,Youping Deng ,Peter R Hoffmann

Selenoprotein I deficiency in T cells promotes differentiation into tolerant phenotypes while decreasing Th17 pathology

T细胞中硒蛋白I缺乏会促进其分化为耐受表型,同时降低Th17病理。

Chi Ma ,FuKun W Hoffmann ,Lance G Nunes ,Frank Urena ,Anastasia Andrukhiv ,Mariana Gerschenson ,Matthew W Pitts ,Peter R Hoffmann

Upregulated ethanolamine phospholipid synthesis via selenoprotein I is required for effective metabolic reprogramming during T cell activation

通过硒蛋白 I 上调乙醇胺磷脂合成是 T 细胞活化过程中有效代谢重编程的必要条件

Chi Ma, FuKun W Hoffmann, Michael P Marciel, Kathleen E Page, Melodie A Williams-Aduja, Ellis N L Akana, Greg S Gojanovich, Mariana Gerschenson, Johann Urschitz, Stefan Moisyadi, Vedbar S Khadka, Sharon Rozovsky, Youping Deng, F David Horgen, Peter R Hoffmann

Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models

多抗原疫苗联合OX40受体激活可延缓恶性间皮瘤生长并提高动物模型的生存率

Hoffmann, Peter R; Hoffmann, Fukun W; Premeaux, Thomas A; Fujita, Tsuyoshi; Soprana, Elisa; Panigada, Maddalena; Chew, Glen M; Richard, Guilhem; Hindocha, Pooja; Menor, Mark; Khadka, Vedbar S; Deng, Youping; Moise, Lenny; Ndhlovu, Lishomwa C; Siccardi, Antonio; Weinberg, Andrew D; De Groot, Anne S; Bertino, Pietro

Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion

靶向半乳糖凝集素-9的C末端可诱导间皮瘤细胞凋亡和M2巨噬细胞耗竭

Pietro Bertino, Thomas A Premeaux, Tsuyoshi Fujita, Brien K Haun, Michael P Marciel, Fukun W Hoffmann, Alan Garcia, Haining Yiang, Sandra Pastorino, Michele Carbone, Toshiro Niki, John Berestecky, Peter R Hoffmann, Lishomwa C Ndhlovu

Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis

硒蛋白 K 缺乏通过减少肿瘤生长和转移所需的钙通量来抑制黑色素瘤

Michael P Marciel, Vedbar S Khadka, Youping Deng, Pascal Kilicaslan, Andrew Pham, Pietro Bertino, Katie Lee, Suzie Chen, Natalija Glibetic, FuKun W Hoffmann, Michelle L Matter, Peter R Hoffmann