Effects of CT-388, a once-weekly signaling-biased dual GLP-1/GIP receptor agonist, on weight loss and glycemic control in preclinical models and participants with obesity
CT-388 是一种每周一次给药的信号传导偏向型双重 GLP-1/GIP 受体激动剂，本研究探讨了其对临床前模型和肥胖患者体重减轻和血糖控制的影响。
期刊:Molecular Metabolism
影响因子:6.6
doi:10.1016/j.molmet.2025.102291
Chakravarthy, Manu V; Rodriguez, Ruben; Hergarden, Anne; Elliott, Michael A; Frias, Juan P; Argüelles-Tello, Federico A; Tenorio, Edgar; Rankin, Jonathan E; Wu, Jingtao; Krishnan, Shyam; Erlanson, Daniel A; Fucini, Raymond V; Bone, Derek; Iwig, Jeffrey S; Acosta, Luis; Untereiner, Ashley; Pant, Asmita; Patton, Avalon; Sanchez-Sanchez, Leyla L; Luo, Jian; Steinberg, Alexandra; Bialonczyk, Damian; Hansen, Stig K
