日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The physical chemistry of interphase loop extrusion

界面环挤出的物理化学

Tortora, Maxime M C; Fudenberg, Geoffrey

The role of cohesin loading at enhancers in the flux of loop extrusion and long-range transcriptional control.

增强子处黏连蛋白的加载在环挤出通量和长程转录控制中的作用。

Anderson Erika C, Rahmaninejad Hadi, Aljahani Abrar, Arnold Emily M, Adachi Annie S, Shah Rini, Hansen Karissa L, Cavka Ivana, Boettiger Alistair N, Fudenberg Geoffrey, Nora Elphège P

Structural variants in human congenital heart disease disrupt distal genomic regulatory contacts of developmental genes.

人类先天性心脏病中的结构变异会破坏发育基因的远端基因组调控联系。

Lee Jodi, Wu Jingshing, Pittman Maureen, Grant Zoe L, Kuang Shuzhen, Quiat Daniel, Morton Sarah U, Fudenberg Geoff, Traglia Michela, Hayes Kelly A, Kumar Ritu, Bruneau Benoit G, Pollard Katherine S

Dynamic barriers modulate cohesin positioning and genome folding at fixed occupancy

动态屏障在固定占据率下调节黏连蛋白定位和基因组折叠

Rahmaninejad, Hadi; Xiao, Yao; Tortora, Maxime M C; Fudenberg, Geoffrey

Recipes and ingredients for deep learning models of 3D genome folding

三维基因组折叠深度学习模型的配方和成分

Smaruj, Paulina N; Xiao, Yao; Fudenberg, Geoffrey

Interpreting the CTCF-mediated sequence grammar of genome folding with AkitaV2

利用 AkitaV2 解读 CTCF 介导的基因组折叠序列语法

Smaruj, Paulina N; Kamulegeya, Fahad; Kelley, David R; Fudenberg, Geoffrey

Reconstructing the 3D genome organization of Neanderthals reveals that chromatin folding shaped phenotypic and sequence divergence

重建尼安德特人的三维基因组结构揭示了染色质折叠如何塑造表型和序列差异。

McArthur, Evonne; Rinker, David C; Cheng, Yang; Wang, Qixuan; Wang, Juan; Gilbertson, Erin N; Fudenberg, Geoff; Pittman, Maureen; Keough, Kathleen; Yue, Feng; Pollard, Katherine S; Capra, John A

Dosage sensitivity of the loop extrusion rate confers tunability to genome folding while creating vulnerability to genetic disruption.

环挤出速率的剂量敏感性赋予基因组折叠的可调性,同时也使其易受基因破坏。

Shah Rini, Tortora Maxime M C, Louafi Nessim, Rahmaninejad Hadi, Hansen Karissa L, Anderson Erika C, Wen David, Giorgetti Luca, Fudenberg Geoffrey, Nora Elphège P

Cooltools: Enabling high-resolution Hi-C analysis in Python

Cooltools:在 Python 中实现高分辨率 Hi-C 分析

Abdennur, Nezar; Abraham, Sameer; Fudenberg, Geoffrey; Flyamer, Ilya M; Galitsyna, Aleksandra A; Goloborodko, Anton; Imakaev, Maxim; Oksuz, Betul A; Venev, Sergey V; Xiao, Yao

Pairtools: From sequencing data to chromosome contacts

Pairtools:从测序数据到染色体接触分析

Abdennur, Nezar; Fudenberg, Geoffrey; Flyamer, Ilya M; Galitsyna, Aleksandra A; Goloborodko, Anton; Imakaev, Maxim; Venev, Sergey V