文献库，生知库 | 链接生命科学的每一步

日期影响因子

Radiosynthesis and Preclinical Evaluation of a Novel (11)C‑Labeled Pyrazolopyrimidine Derivative for Positron Emission Tomography Imaging of Phosphodiesterase 2A

一种新型（11）C标记的吡唑并嘧啶衍生物的放射合成及临床前评价，用于磷酸二酯酶2A的正电子发射断层扫描成像

期刊:ACS Medicinal Chemistry Letters

doi:10.1021/acsmedchemlett.5c00649

Li, Yinlong; Mori, Wakana; Song, Zhendong; Yamasaki, Tomoteru; Zhao, Taoqian; Chen, Jiahui; Zhang, Yiding; Zhou, Xin; Xie, Lin; Kokufuta, Tomomi; Hu, Kuan; Hu, Qilong; Fujinaga, Masayuki; Li, Xiaoyan; Kumata, Katsushi; Li, Chongjiao; Sun, Zhenkun; Gao, Yabiao; Hoyle, Danielle E; Patel, Jimmy S; Yuan, Hongjie; Zhang, Ming-Rong; Liang, Steven H

发表日期：2026

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l-[5-(11)C]Glutamine PET imaging noninvasively tracks dynamic responses of glutaminolysis in non-alcoholic steatohepatitis.

l-[5-(11)C]谷氨酰胺 PET 成像可无创地追踪非酒精性脂肪性肝炎中谷氨酰胺分解的动态反应

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2024.07.023

Zhang Yiding, Xie Lin, Fujinaga Masayuki, Kurihara Yusuke, Ogawa Masanao, Kumata Katsushi, Mori Wakana, Kokufuta Tomomi, Nengaki Nobuki, Wakizaka Hidekatsu, Luo Rui, Wang Feng, Hu Kuan, Zhang Ming-Rong

发表日期：2025

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A (211)At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy

一种(211)At标记的mGluR1抑制剂可诱导癌细胞衰老，从而产生持久的抗肿瘤疗效。

期刊:Cell Reports Medicine

影响因子:10.6

doi:10.1016/j.xcrm.2025.101945

Xie, Lin; Zhang, Lulu; Hu, Kuan; Hanyu, Masayuki; Zhang, Yiding; Fujinaga, Masayuki; Minegishi, Katsuyuki; Ohkubo, Takayuki; Nagatsu, Kotaro; Jiang, Cuiping; Shimokawa, Takashi; Ashisuke, Kazuma; Okonogi, Noriyuki; Yamada, Shigeru; Wang, Feng; Wang, Rui; Zhang, Ming-Rong

细胞生物学

发表日期：2025

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Discovery of Pyrazole-Based Positron Emission Tomography Agent that Maps Histone Deacetylase 6 (HDAC6) in the Nonhuman Primate Brain

发现一种基于吡唑的正电子发射断层扫描显像剂，可用于绘制非人灵长类动物脑内组蛋白去乙酰化酶6 (HDAC6) 的分布图

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c02216

Yamasaki, Tomoteru; Ohyabu, Norio; Wakabayashi, Takeshi; Ibáñez, Ignacio; Iwanaga, Kouichi; Yamamoto, Satoshi; Hattori, Masahiko; Sugita, Taku; Terada, Michiko; Onishi, Tomohiro; Sato, Sho; Kosugi, Yohei; Takano, Akihiro; McQuade, Paul; Maru, Takamitsu; Inui, Naomi; Fujinaga, Masayuki; Mori, Wakana; Nagai, Yuji; Seki, Chie; Uchida, Shoko; Minamimoto, Takafumi; Higuchi, Makoto; Fushimi, Makoto; Zhang, Ming-Rong

发表日期：2025

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Radiosynthesis and Preclinical Evaluation of a Carbon-11 Labeled Phosphodiesterase 7 Inhibitor for PET Neuroimaging

用于PET神经影像的碳-11标记磷酸二酯酶7抑制剂的放射合成和临床前评价

期刊:ACS Medicinal Chemistry Letters

doi:10.1021/acsmedchemlett.5c00385

Xiao, Zhiwei; Sun, Jiyun; Fujinaga, Masayuki; Wei, Huiyi; Zhao, Chunyu; Haider, Achi; Van, Richard; Kuang, Shi; Yamasaki, Tomoteru; Zhang, Yiding; Rong, Jian; Hu, Kuan; Chen, Jiahui; Leon, Erick Calderon; Mori, Wakana; Xie, Lin; Wei, Junjie; Xu, Yi; Shao, Yihan; Zhang, Han-Ting; Xu, Ying; Ran, Chongzhao; Lloyd, Kc Kent; Wang, Lu; Zhang, Ming-Rong; Liang, Steven H

发表日期：2025

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Evaluation of in vivo and in vitro binding property of a novel candidate PET tracer for CSF1R imaging and comparison with two currently-used CSF1R-PET tracers

评估一种新型候选CSF1R成像PET示踪剂的体内和体外结合特性，并与两种目前使用的CSF1R-PET示踪剂进行比较

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-025-00345-8

Rui, Xiyan; Ding, Yuzhou; Zhang, Nailian; Zhao, Xinran; Seki, Chie; Yamasaki, Tomoteru; Fujinaga, Masayuki; Zhang, Ming-Rong; Qian, Jun; Ji, Bin; Zhou, Rong

发表日期：2025

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Evaluation of in-vivo and in-vitro binding property of a novel PET tracer for CSF1R imaging and comparison with two currently-used CSF1R-PET tracers

评估一种新型CSF1R成像PET示踪剂的体内和体外结合特性，并与两种目前使用的CSF1R-PET示踪剂进行比较

doi:10.21203/rs.3.rs-6194254/v1

Rui, Xiyan; Ding, Yuzhou; Zhang, Nailian; Zhao, Xinran; Seki, Chie; Yamasaki, Tomoteru; Fujinaga, Masayuki; Zhang, Ming-Rong; Qian, Jun; Ji, Bin; Zhou, Rong

发表日期：2025

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Potential for in vivo visualization of intracellular pH gradient in the brain using PET imaging

利用PET成像技术在脑内细胞内pH梯度进行体内可视化的潜力

期刊:Brain Communications

影响因子:4.5

doi:10.1093/braincomms/fcae172

Yamasaki, Tomoteru; Mori, Wakana; Ohkubo, Takayuki; Hiraishi, Atsuto; Zhang, Yiding; Kurihara, Yusuke; Nengaki, Nobuki; Tashima, Hideaki; Fujinaga, Masayuki; Zhang, Ming-Rong

细胞生物学

发表日期：2024

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Development of a Candidate (11)C‑Labeled Selective Phosphodiesterase 1 Radioligand for Positron Emission Tomography

开发用于正电子发射断层扫描的候选（11）C标记选择性磷酸二酯酶1放射性配体

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c03214

Rong, Jian; Yamasaki, Tomoteru; Chen, Jiahui; Kumata, Katsushi; Zhao, Chunyu; Fujinaga, Masayuki; Hu, Kuan; Mori, Wakana; Zhang, Yiding; Xie, Lin; Chaudhary, Ahmad F; Zhou, Xin; Zhang, Wei; Gao, Yabiao; Zhang, Kuo; Patel, Jimmy S; Song, Zhendong; Collier, Thomas L; Yuan, Hongjie; Ran, Chongzhao; Haider, Achi; Li, Yinlong; Zhang, Ming-Rong; Liang, Steven

发表日期：2024

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Radiosynthesis and preclinical evaluation of a carbon-11 labeled PET ligand for imaging metabotropic glutamate receptor 7

碳-11标记PET配体的放射合成及临床前评估用于代谢型谷氨酸受体7的成像

期刊:American Journal of Nuclear Medicine and Molecular Imaging

影响因子:1.8

doi:10.62347/PUAI9230

Li, Yinlong; Xiao, Zhiwei; Mori, Wakana; Sun, Jiyun; Yamasaki, Tomoteru; Rong, Jian; Fujinaga, Masayuki; Chen, Jiahui; Kumata, Katsushi; Zhao, Chunyu; Zhang, Yiding; Collier, Thomas L; Hu, Kuan; Xie, Lin; Zhou, Xin; Zhang, Wei; Song, Zhendong; Gao, Yabiao; Sun, Zhenkun; Zhang, Kuo; Patel, Jimmy S; Ran, Chongzhao; Chaudhary, Ahmad; Sheffler, Douglas J; Cosford, Nicholas Dp; Zhang, Linqi; Zhai, Chuangyan; Haider, Ahmed; Yuan, Hongjie; Zhang, Ming-Rong; Liang, Steven H

发表日期：2024

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