Funakoshi-Tago相关文献与解析，生知库 | 链接生命科学的每一步

Ikeda, Junji; Kunimoto, Hiroyoshi; Saito, Yusuke; Tsujimoto, Shin-Ichi; Takeuchi, Masanobu; Miura, Ayaka; Kurosawa, Takayuki; Murakami, Koichi; Kato, Ikuma; Funakoshi-Tago, Megumi; Yokoyama, Akihiko; Shiba, Norio; Adachi, Souichi; Tomizawa, Daisuke; Tamura, Tomohiko; Ito, Shuichi; Nakajima, Hideaki

白血病

PRDM1

代谢重编程

代谢

发表日期：2025

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Development of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, and its Anti-Inflammatory Effects

基于萘-2-乙酰胺骨架的Keap1-Nrf2蛋白-蛋白相互作用抑制剂的开发及其对细胞内Nrf2的激活作用及其抗炎作用

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202500474

Yasuda, Daisuke; Toyoshima, Kai; Kojima, Koujin; Ishida, Hanako; Kaitoh, Kazuma; Imamura, Riyo; Kanamitsu, Kayoko; Kojima, Hirotatsu; Funakoshi-Tago, Megumi; Osawa, Masanori; Ohe, Tomoyuki; Hirano, Tomoya

细胞生物学

发表日期：2025

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FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5

FL118 是一种通过靶向 RNA 解旋酶 DDX5 来治疗对 BCR-ABL 抑制剂有耐药性的慢性粒细胞白血病的有效治疗剂

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms25073693

Kengo Takeda, Satoshi Ohta, Miu Nagao, Erika Kobayashi, Kenji Tago, Megumi Funakoshi-Tago

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation

橙皮素治疗可减弱晶状体蛋白的糖化和晚期糖化终产物的生成

期刊:Molecular Medicine Reports

影响因子:3.4

doi:10.3892/mmr.2023.12990

Yuri Doki #, Yosuke Nakazawa #, Naoki Morishita, Shin Endo, Noriaki Nagai, Naoki Yamamoto, Hiroomi Tamura, Megumi Funakoshi-Tago

信号转导

发表日期：2023

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Effect of Alpha-Glucosyl-Hesperidin Consumption on Lens Sclerosis and Presbyopia

服用α-葡萄糖基橙皮苷对晶状体硬化和老花眼的影响

期刊:Cells

影响因子:5.1

doi:10.3390/cells10020382

Yosuke Nakazawa, Yuri Doki, Yuki Sugiyama, Ryota Kobayashi, Noriaki Nagai, Naoki Morisita, Shin Endo, Megumi Funakoshi-Tago, Hiroomi Tamura

信号转导

发表日期：2021

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EBP2, a novel NPM-ALK-interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53

EBP2 是一种位于核仁中的新型 NPM-ALK 相互作用蛋白，它通过调节肿瘤抑制因子 p53 促进 ALCL 细胞增殖

期刊:Molecular Oncology

影响因子:5

doi:10.1002/1878-0261.12822

Yuki Uchihara, Kenji Tago, Hiroomi Tamura, Megumi Funakoshi-Tago

K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors

K15 启动子驱动的 NKIRAS 强制表达对 DMBA/TPA 诱发的皮肤肿瘤发展具有肿瘤抑制活性

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-00200-1

Kenji Tago, Satoshi Ohta, Chihiro Aoki-Ohmura, Megumi Funakoshi-Tago, Miho Sashikawa, Takeshi Matsui, Yuki Miyamoto, Taeko Wada, Tomoyuki Oshio, Mayumi Komine, Jitsuhiro Matsugi, Yusuke Furukawa, Mamitaro Ohtsuki, Junji Yamauchi, Ken Yanagisawa

Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells

咖啡煎剂增强他莫昔芬对MCF-7细胞的促凋亡活性

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-020-76445-z

Funakoshi-Tago, Megumi; Tago, Kenji; Li, Chin; Hokimoto, Shingo; Tamura, Hiroomi

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

汉方药六味丸、八味地黄丸和五车神气丸能显著抑制胰高血糖素诱导的CREB活化。

期刊:Heliyon

影响因子:3.6

doi:10.1016/j.heliyon.2020.e03598

Funakoshi-Tago, Megumi; Yu, Seisho; Kushida, Akira; Takeuchi, Kazusane; Tamura, Hiroomi

CREB

发表日期：2020

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Oncogenic Ras mutant causes the hyperactivation of NF-κB via acceleration of its transcriptional activation

致癌性Ras突变体通过加速NF-κB的转录激活，导致NF-κB过度激活。

期刊:Molecular Oncology

影响因子:5

doi:10.1002/1878-0261.12580.

Kenji Tago,Megumi Funakoshi-Tago,Satoshi Ohta,Hirotoshi Kawata,Hiroshi Saitoh,Hisanaga Horie,Chihiro Aoki-Ohmura,Junji Yamauchi,Akira Tanaka,Jitsuhiro Matsugi,Ken Yanagisawa

Metabolic reprogramming by PRDM16 drives cytarabine resistance in acute myeloid leukemia

PRDM16介导的代谢重编程驱动急性髓系白血病产生阿糖胞苷耐药性

Development of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, and its Anti-Inflammatory Effects

基于萘-2-乙酰胺骨架的Keap1-Nrf2蛋白-蛋白相互作用抑制剂的开发及其对细胞内Nrf2的激活作用及其抗炎作用

FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5

FL118 是一种通过靶向 RNA 解旋酶 DDX5 来治疗对 BCR-ABL 抑制剂有耐药性的慢性粒细胞白血病的有效治疗剂

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation

橙皮素治疗可减弱晶状体蛋白的糖化和晚期糖化终产物的生成

Effect of Alpha-Glucosyl-Hesperidin Consumption on Lens Sclerosis and Presbyopia

服用α-葡萄糖基橙皮苷对晶状体硬化和老花眼的影响

EBP2, a novel NPM-ALK-interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53

EBP2 是一种位于核仁中的新型 NPM-ALK 相互作用蛋白，它通过调节肿瘤抑制因子 p53 促进 ALCL 细胞增殖

K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors

K15 启动子驱动的 NKIRAS 强制表达对 DMBA/TPA 诱发的皮肤肿瘤发展具有肿瘤抑制活性

Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells

咖啡煎剂增强他莫昔芬对MCF-7细胞的促凋亡活性

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

汉方药六味丸、八味地黄丸和五车神气丸能显著抑制胰高血糖素诱导的CREB活化。

Oncogenic Ras mutant causes the hyperactivation of NF-κB via acceleration of its transcriptional activation

致癌性Ras突变体通过加速NF-κB的转录激活，导致NF-κB过度激活。