日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Author Correction: Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers

作者更正:IAG933 通过直接和选择性地药理学手段破坏 YAP-TEAD 界面,从而抑制 Hippo 依赖性和 RAS-MAPK 改变的癌症。

Chapeau, Emilie A; Sansregret, Laurent; Galli, Giorgio G; Chène, Patrick; Wartmann, Markus; Mourikis, Thanos P; Jaaks, Patricia; Baltschukat, Sabrina; Barbosa, Ines A M; Bauer, Daniel; Brachmann, Saskia M; Delaunay, Clara; Estadieu, Claire; Faris, Jason E; Furet, Pascal; Harlfinger, Stefanie; Hueber, Andreas; Jiménez Núñez, Eloísa; Kodack, David P; Mandon, Emeline; Martin, Typhaine; Mesrouze, Yannick; Romanet, Vincent; Scheufler, Clemens; Sellner, Holger; Stamm, Christelle; Sterker, Dario; Tordella, Luca; Hofmann, Francesco; Soldermann, Nicolas; Schmelzle, Tobias

Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface

结合态固有无序蛋白YAP对YAP:TEAD界面突变的适应

Mesrouze, Yannick; Bokhovchuk, Fedir; Izaac, Aude; Meyerhofer, Marco; Zimmermann, Catherine; Fontana, Patrizia; Schmelzle, Tobias; Erdmann, Dirk; Furet, Pascal; Kallen, Joerg; Chène, Patrick

2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4

2-甲酰基吡啶基脲类化合物作为成纤维细胞生长因子受体4的高选择性可逆共价抑制剂

Knoepfel, Thomas; Furet, Pascal; Mah, Robert; Buschmann, Nicole; Leblanc, Catherine; Ripoche, Sebastien; Graus-Porta, Diana; Wartmann, Markus; Galuba, Inga; Fairhurst, Robin A

Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region

通过靶向ATP结合口袋中铰链区选择性抑制成纤维细胞生长因子受体4的方法

Fairhurst, Robin A; Knoepfel, Thomas; Leblanc, Catherine; Buschmann, Nicole; Gaul, Christoph; Blank, Jutta; Galuba, Inga; Trappe, Jörg; Zou, Chao; Voshol, Johannes; Genick, Christine; Brunet-Lefeuvre, Peggy; Bitsch, Francis; Graus-Porta, Diana; Furet, Pascal

Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097

更正:一组独特的 p53 靶基因可预测对选择性 p53-HDM2 抑制剂 NVP-CGM097 的反应。

Jeay, Sébastien; Gaulis, Swann; Ferretti, Stéphane; Bitter, Hans; Ito, Moriko; Valat, Thérèse; Murakami, Masato; Ruetz, Stephan; Guthy, Daniel A; Rynn, Caroline; Jensen, Michael R; Wiesmann, Marion; Kallen, Joerg; Furet, Pascal; Gessier, François; Holzer, Philipp; Masuya, Keiichi; Würthner, Jens; Halilovic, Ensar; Hofmann, Francesco; Sellers, William R; Graus Porta, Diana

Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo

高效、选择性强且口服生物利用度高的VPS34抑制剂为体内自噬调控提供了化学工具

Honda, Ayako; Harrington, Edmund; Cornella-Taracido, Ivan; Furet, Pascal; Knapp, Mark S; Glick, Meir; Triantafellow, Ellen; Dowdle, William E; Wiedershain, Dmitri; Maniara, Wieslawa; Moore, Christine; Finan, Peter M; Hamann, Lawrence G; Firestone, Brant; Murphy, Leon O; Keaney, Erin P

A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097

一组独特的p53靶基因预测了对选择性p53-HDM2抑制剂NVP-CGM097的反应

Jeay, Sébastien; Gaulis, Swann; Ferretti, Stéphane; Bitter, Hans; Ito, Moriko; Valat, Thérèse; Murakami, Masato; Ruetz, Stephan; Guthy, Daniel A; Rynn, Caroline; Jensen, Michael R; Wiesmann, Marion; Kallen, Joerg; Furet, Pascal; Gessier, François; Holzer, Philipp; Masuya, Keiichi; Würthner, Jens; Halilovic, Ensar; Hofmann, Francesco; Sellers, William R; Graus Porta, Diana

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis.

小分子特异性 EphB4 激酶抑制剂 NVP-BHG712 可抑制 VEGF 驱动的血管生成

Martiny-Baron Georg, Holzer Philipp, Billy Eric, Schnell Christian, Brueggen Joseph, Ferretti Mireille, Schmiedeberg Niko, Wood Jeanette M, Furet Pascal, Imbach Patricia

Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison

新型第一代和第二代FLT3抑制剂的抗白血病作用:结构-亲和力比较

Weisberg, Ellen; Roesel, Johannes; Furet, Pascal; Bold, Guido; Imbach, Patricia; Flörsheimer, Andreas; Caravatti, Georgio; Jiang, Jingrui; Manley, Paul; Ray, Arghya; Griffin, James D