日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6

色氨酸-75 是一种低能通道门控残基,可促进细胞色素 P450 2D6 中的底物出入

Kevin D McCarty, Samuel A Ratliff, Kyle A Furge, Laura Lowe Furge

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma

药物抑制 MEK 信号可防止犬血管肉瘤的生长

Nicholas J Andersen, Brian J Nickoloff, Karl J Dykema, Elissa A Boguslawski, Roman I Krivochenitser, Roe E Froman, Michelle J Dawes, Laurence H Baker, Dafydd G Thomas, Debra A Kamstock, Barbara E Kitchell, Kyle A Furge, Nicholas S Duesbery

Gene expression in archived newborn blood spots distinguishes infants who will later develop cerebral palsy from matched controls

存档的新生儿血斑样本中的基因表达可以区分后来会患上脑瘫的婴儿和匹配的对照组婴儿。

Ho, Nhan Thi; Furge, Kyle; Fu, Wenjiang; Busik, Julia; Khoo, Sok Kean; Lu, Qing; Lenski, Madeleine; Wirth, Julia; Hurvitz, Edward; Dodge, Nancy; Resau, James; Paneth, Nigel

Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy

HGF过表达促进HBV诱导的肝细胞癌进展,是Met靶向治疗的有效指标

Xie, Qian; Su, Yanli; Dykema, Karl; Johnson, Jennifer; Koeman, Julie; De Giorgi, Valeria; Huang, Alan; Schlegel, Robert; Essenburg, Curt; Kang, Liang; Iwaya, Keiichi; Seki, Shuhji; Khoo, Sok Kean; Zhang, Boheng; Buonaguro, Franco; Marincola, Francesco M; Furge, Kyle; Vande Woude, George F; Shinomiya, Nariyoshi

Evaluation of sex-specific gene expression in archived dried blood spots (DBS)

对存档的干血斑(DBS)中性别特异性基因表达的评估

Resau, James H; Ho, Nhan T; Dykema, Karl; Faber, Matthew S; Busik, Julia V; Nickolov, Radoslav Z; Furge, Kyle A; Paneth, Nigel; Jewell, Scott; Khoo, Sok Kean

Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation

甲基化和组蛋白去乙酰化抑制剂对MIG-6表达的癌症型调控

Zhang, Yu-Wen; Staal, Ben; Dykema, Karl J; Furge, Kyle A; Vande Woude, George F

Genome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysis

利用源自单样本分析的关联性判定模型,进行全基因组基因与细胞功能的匹配

Klomp, Jeff A; Furge, Kyle A

Molecular analysis and modeling of inactivation of human CYP2D6 by four mechanism based inactivators

四种基于机制的灭活剂对人CYP2D6失活的分子分析和建模

Livezey, Mara; Nagy, Leslie D; Diffenderfer, Laura E; Arthur, Evan J; Hsi, David J; Holton, Jeffrey M; Furge, Laura Lowe

Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors

肾肿瘤中富马酸水合酶的失活:HIF1α、NRF2 和转录因子的“隐蔽靶点”

Ooi, Aikseng; Furge, Kyle A

Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing

通过靶向深度测序揭示胃癌激酶组的遗传和结构变异

Zang, Zhi Jiang; Ong, Choon Kiat; Cutcutache, Ioana; Yu, Willie; Zhang, Shen Li; Huang, Dachuan; Ler, Lian Dee; Dykema, Karl; Gan, Anna; Tao, Jiong; Lim, Siyu; Liu, Yujing; Futreal, P Andrew; Grabsch, Heike; Furge, Kyle A; Goh, Liang Kee; Rozen, Steve; Teh, Bin Tean; Tan, Patrick