Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance.
共价加合物 Grob 断裂是 LSD1 去甲基酶特异性抑制剂作用机制和耐药性的基础
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57477-3
Waterbury Amanda L, Caroli Jonatan, Zhang Olivia, Tuttle Paloma R, Liu Chao, Li Jiaming, Park Ji Sung, Hoenig Samuel M, Barone Marco, Furui Airi, Mattevi Andrea, Liau Brian B
