14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in T(C)2 and CD8(+) lymphocytes from patients with scleroderma
14-3-3z 可螯合胞质 T-bet,上调硬皮病患者 T(C)2 和 CD8(+) 淋巴细胞中的 IL-13 水平。
期刊:Journal of Allergy and Clinical Immunology
影响因子:11.2
doi:10.1016/j.jaci.2017.10.029
Cascio, Sandra; Medsger, Thomas A Jr; Hawse, William F; Watkins, Simon C; Milcarek, Christine; Moreland, Larry W; Lafyatis, Robert A; Fuschiotti, Patrizia
T细胞
CD8
T-bet
IL-13
系统性硬化症
细胞生物学