Enhancing human NK cell antitumor function by knocking out SMAD4 to counteract TGFβ and activin A suppression.
通过敲除 SMAD4 来对抗 TGFβ 和激活素 A 的抑制，从而增强人类 NK 细胞的抗肿瘤功能
期刊:Nature Immunology
影响因子:27.6
doi:10.1038/s41590-025-02103-z
Rea Anna, Santana-Hernández Sara, Villanueva Javier, Sanvicente-GarcÃa Marta, Cabo Mariona, Suarez-Olmos Jesús, Quimis Fabricio, Qin Mengjuan, Llorens Eduard, Blasco-Benito Sandra, Torralba-Raga Lamberto, Perez Lorena, Bhattarai Bishan, Alari-Pahissa Elisenda, Georgoudaki Anna-Maria, Balaguer Francesc, Juan Manel, Pardo Julián, Celià -Terrassa Toni, Rovira Ana, Möker Nina, Zhang Congcong, Colonna Marco, Spanholtz Jan, Malmberg Karl-Johan, Montagut Clara, Albanell Joan, Güell Marc, López-Botet Miguel, Muntasell Aura
