Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro
1p/19q 缺失的少突胶质细胞肿瘤中经常发生启动子高甲基化导致 PRDX1 下调，并增加体外 Hs683 胶质瘤细胞的放射和化学敏感性
期刊:Oncogene
影响因子:6.9
doi:10.1038/onc.2011.513
L M Dittmann, A Danner, J Gronych, M Wolter, K Stühler, M Grzendowski, N Becker, J Bageritz, V Goidts, G Toedt, J Felsberg, M C Sabel, S Barbus, G Reifenberger, P Lichter, B Tews
