Gabaev相关文献与解析，生知库 | 链接生命科学的每一步

Greaves, Daniel E; Gabaev, Ildar; Williamson, James C; Bloor, Stuart; Martinez Cuesta, Sergio; Matheson, Nicholas J; Frappier, Lori; Déjardin, Jérôme; Lehner, Paul J

微生物学

信号转导

发表日期：2026

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CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex

CRISPR-Cas9基因筛选揭示了Elongin BC-VHL复合物对TMPRSS2的调控作用

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-025-95644-0

Ildar Gabaev ，Alexandra Rowland ，Emilija Jovanovic ，Christian M Gawden-Bone ，Thomas W M Crozier ，Ana Teixeira-Silva ，Edward J D Greenwood ，Pehuén Pereyra Gerber ，Niek Wit ，James A Nathan ，Nicholas J Matheson ，Paul J Lehner

LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein

LRRC15 介导与 SARS-CoV-2 刺突蛋白的附加相互作用

期刊:PLoS Biology

影响因子:7.8

doi:10.1371/journal.pbio.3001959

Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright

A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection

用于真实 SARS-CoV-2 感染的蛋白酶激活发光生物传感器和报告细胞系

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1010265

Pehuén Pereyra Gerber, Lidia M Duncan, Edward Jd Greenwood, Sara Marelli, Adi Naamati, Ana Teixeira-Silva, Thomas Wm Crozier, Ildar Gabaev, Jun R Zhan, Thomas E Mulroney, Emily C Horner, Rainer Doffinger, Anne E Willis, James Ed Thaventhiran, Anna V Protasio, Nicholas J Matheson

Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion

SARS-CoV-2 感染原代人气道纤毛细胞和肺上皮细胞的定量蛋白质组学分析证明了 SARS-CoV-2 先天免疫逃避的有效性

期刊:Wellcome Open Research

影响因子:

doi:10.12688/wellcomeopenres.17946.1

Thomas W M Crozier #, Edward J D Greenwood #, James C Williamson #, Wenrui Guo, Linsey M Porter, Ildar Gabaev, Ana Teixeira-Silva, Guinevere L Grice, Arthur Wickenhagen, Richard J Stanton, Eddie C Y Wang, Sam J Wilson, Nicholas J Matheson, James A Nathan, Frank McCaughan, Paul J Lehner

Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation

定量蛋白质组学分析揭示了人内皮细胞裂解性KSHV感染的病毒免疫调节靶点

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2020.108249

Ildar Gabaev ，James C Williamson ，Thomas W M Crozier ，Thomas F Schulz ，Paul J Lehner

Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Is Independent of Anaphase-Promoting Complex Activity

卡波西肉瘤相关疱疹病毒裂解复制与后期促进复合物活性无关

期刊:Journal of Virology

影响因子:4

doi:10.1128/JVI.02079-19

Endrit Elbasani, Silvia Gramolelli, Thomas Günther, Ildar Gabaev, Adam Grundhoff, Päivi M Ojala

A Prominent Role of the Human Cytomegalovirus UL8 Glycoprotein in Restraining Proinflammatory Cytokine Production by Myeloid Cells at Late Times during Infection

人巨细胞病毒UL8糖蛋白在感染后期抑制髓系细胞产生促炎细胞因子方面发挥着重要作用

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.02229-17

Pérez-Carmona, Natàlia; Martínez-Vicente, Pablo; Farré, Domènec; Gabaev, Ildar; Messerle, Martin; Engel, Pablo; Angulo, Ana

The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion

人类巨细胞病毒糖蛋白 pUL11 通过 CD45 诱导 T 细胞 IL-10 分泌

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1006454

Jasmin Zischke, Panagiota Mamareli, Claudia Pokoyski, Ildar Gabaev, Sabine Buyny, Roland Jacobs, Christine S Falk, Matthias Lochner, Tim Sparwasser, Thomas F Schulz, Penelope C Kay-Fedorov

Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV

来自脐带血和成人血液的工程树突状细胞可加速针对 HCMV 的效应 T 细胞免疫重建

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:

doi:10.1038/mtm.2014.60

Anusara Daenthanasanmak, Gustavo Salguero, Bala Sai Sundarasetty, Claudia Waskow, Kadriye Nehir Cosgun, Carlos A Guzman, Peggy Riese, Laura Gerasch, Andreas Schneider, Alexandra Ingendoh, Martin Messerle, Ildar Gabaev, Benno Woelk, Eliana Ruggiero, Manfred Schmidt, Christof von Kalle, Constanca Figu

Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation

位点特异性蛋白质组学鉴定出Epstein-Barr病毒裂解性再激活的新型调控因子

CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex

CRISPR-Cas9基因筛选揭示了Elongin BC-VHL复合物对TMPRSS2的调控作用

LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein

LRRC15 介导与 SARS-CoV-2 刺突蛋白的附加相互作用

A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection

用于真实 SARS-CoV-2 感染的蛋白酶激活发光生物传感器和报告细胞系

Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion

SARS-CoV-2 感染原代人气道纤毛细胞和肺上皮细胞的定量蛋白质组学分析证明了 SARS-CoV-2 先天免疫逃避的有效性

Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation

定量蛋白质组学分析揭示了人内皮细胞裂解性KSHV感染的病毒免疫调节靶点

Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Is Independent of Anaphase-Promoting Complex Activity

卡波西肉瘤相关疱疹病毒裂解复制与后期促进复合物活性无关

A Prominent Role of the Human Cytomegalovirus UL8 Glycoprotein in Restraining Proinflammatory Cytokine Production by Myeloid Cells at Late Times during Infection

人巨细胞病毒UL8糖蛋白在感染后期抑制髓系细胞产生促炎细胞因子方面发挥着重要作用

The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion

人类巨细胞病毒糖蛋白 pUL11 通过 CD45 诱导 T 细胞 IL-10 分泌

Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV

来自脐带血和成人血液的工程树突状细胞可加速针对 HCMV 的效应 T 细胞免疫重建