日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Massively parallel characterization of CYP2C9 variant enzyme activity and abundance

大规模并行表征 CYP2C9 变体酶活性和丰度

Clara J Amorosi, Melissa A Chiasson, Matthew G McDonald, Lai Hong Wong, Katherine A Sitko, Gabriel Boyle, John P Kowalski, Allan E Rettie, Douglas M Fowler, Maitreya J Dunham

Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons

α-突触核蛋白在小鼠和原代神经元中对阿尔茨海默病表型的双向调节

Shahzad S Khan, Michael LaCroix, Gabriel Boyle, Mathew A Sherman, Jennifer L Brown, Fatou Amar, Jacqeline Aldaco, Michael K Lee, George S Bloom, Sylvain E Lesné

Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits

寡聚 α-突触核蛋白诱导的突触蛋白选择性降低加剧了记忆缺陷

Megan E Larson, Susan J Greimel, Fatou Amar, Michael LaCroix, Gabriel Boyle, Mathew A Sherman, Hallie Schley, Camille Miel, Julie A Schneider, Rakez Kayed, Fabio Benfenati, Michael K Lee, David A Bennett, Sylvain E Lesné

The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation

淀粉样蛋白-β 寡聚体 Aβ*56 诱导神经信号的特定改变,导致 tau 磷酸化和聚集

Fatou Amar, Mathew A Sherman, Travis Rush, Megan Larson, Gabriel Boyle, Liu Chang, Jürgen Götz, Alain Buisson, Sylvain E Lesné