日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA

在 12 月龄 ATM 基因缺失小鼠的小脑萎缩中,转录组上调涉及大多数神经传递和神经肽通路,而下调则显著影响 Itpr1、Usp2 和非编码 RNA

Marina Reichlmeir, Júlia Canet-Pons, Gabriele Koepf, Wasifa Nurieva, Ruth Pia Duecker, Claudia Doering, Kathryn Abell, Jana Key, Matthew P Stokes, Stefan Zielen, Ralf Schubert, Zoltán Ivics, Georg Auburger

Translation Fidelity and Respiration Deficits in CLPP-Deficient Tissues: Mechanistic Insights from Mitochondrial Complexome Profiling

CLPP 缺陷组织中的翻译保真度和呼吸缺陷:来自线粒体复合体分析的机制见解

Jana Key, Suzana Gispert, Gabriele Koepf, Julia Steinhoff-Wagner, Marina Reichlmeir, Georg Auburger

CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2

CLPP 耗竭导致双线期停滞;潜在的睾丸线粒体功能障碍与 Perrault 蛋白 ERAL1、PEO1 和 HARS2 的积累有关

Jana Key, Suzana Gispert, Lieke Koornneef, Esther Sleddens-Linkels, Aneesha Kohli, Sylvia Torres-Odio, Gabriele Koepf, Shady Amr, Marina Reichlmeir, Patrick N Harter, Andrew Phillip West, Christian Münch, Willy M Baarends, Georg Auburger

Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA

肽酶 ClpP 失活导致线粒体解聚酶 ClpX 及其相互作用的核蛋白和线粒体 DNA 的初级积累

Jana Key, Sylvia Torres-Odio, Nina C Bach, Suzana Gispert, Gabriele Koepf, Marina Reichlmeir, A Phillip West, Holger Prokisch, Peter Freisinger, William G Newman, Stavit Shalev, Stephan A Sieber, Ilka Wittig, Georg Auburger

Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse

核 DNAJA3 的存在增加以及细胞浆 STAT1 和核酸传感器的上调触发了 ClpP 缺陷小鼠的先天免疫

Antonia Maletzko #, Jana Key #, Ilka Wittig, Suzana Gispert, Gabriele Koepf, Júlia Canet-Pons, Sylvia Torres-Odio, A Phillip West, Georg Auburger

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence

铁稳态机制的系统研究表明,PINK1 缺失可改变铁蛋白超家族和核苷酸监视调节

Jana Key, Nesli Ece Sen, Aleksandar Arsović, Stella Krämer, Robert Hülse, Natasha Nadeem Khan, David Meierhofer, Suzana Gispert, Gabriele Koepf, Georg Auburger