Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition
Aurora B 抑制剂促进 RB 低磷酸化和衰老,且该过程不依赖于 p53 依赖的 CDK2/4 抑制。
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-024-07204-5
Vora, Shivam; Andrew, Ariel; Kumar, Ramyashree Prasanna; Nazareth, Deborah; Bonfim-Melo, Alexis; Lim, Yoon; Ong, Xin Yee; Fernando, Madushan; He, Yaowu; Hooper, John D; McMillan, Nigel Aj; Urosevic, Jelena; Travers, Jon; Saeh, Jamal; Kumar, Sharad; Jones, Mathew Jk; Gabrielli, Brian