Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells
G-四链体配体对ATM/自噬通路的调控作用会影响癌细胞衰老和凋亡之间的平衡。
期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gkz095
Jennifer Beauvarlet ,Paul Bensadoun ,Elodie Darbo ,Gaelle Labrunie ,Benoît Rousseau ,Elodie Richard ,Irena Draskovic ,Arturo Londono-Vallejo ,Jean-William Dupuy ,Rabindra Nath Das ,Aurore Guédin ,Guillaume Robert ,Francois Orange ,Sabrina Croce ,Valerie Valesco ,Pierre Soubeyran ,Kevin M Ryan ,Jean-Louis Mergny ,Mojgan Djavaheri-Mergny
凋亡
肿瘤免疫
自噬
细胞生物学
ATM
信号转导
肿瘤
细胞衰老
衰老
表观遗传
