Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer
致癌性β-catenin刺激AKT2-CAD介导的嘧啶合成是肝癌中可靶向的脆弱点。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2202157119
Liu, Fangming; Gai, Xiaochen; Wu, Yuting; Zhang, Baohui; Wu, Xiaoyu; Cheng, Rongrong; Tang, Bufu; Shang, Kezhuo; Zhao, Na; Deng, Weiwei; Chen, Jie; Zhang, Zhengyi; Gu, Song; Zheng, Liang; Zhang, Hongbing