Discovery of 2-(((1r,4r)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.
发现 2-(((1r,4r)-4-(((4-氯苯基)(苯基)氨基甲酰基)氧基)甲基)环己基)甲氧基)乙酸酯（Ralinepag）：一种口服活性前列环素受体激动剂，用于治疗肺动脉高压
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.6b00871
Tran Thuy-Anh, Kramer Bryan, Shin Young-Jun, Vallar Pureza, Boatman P Douglas, Zou Ning, Sage Carleton R, Gharbaoui Tawfik, Krishnan Ashwin, Pal Biman, Shakya Sagar R, Garrido Montalban Antonio, Adams John W, Ramirez Juan, Behan Dominic P, Shifrina Anna, Blackburn Anthony, Leakakos Tina, Shi Yunqing, Morgan Michael, Sadeque Abu, Chen Weichao, Unett David J, Gaidarov Ibragim, Chen Xiaohua, Chang Steve, Shu Hsin-Hui, Tung Shiu-Feng, Semple Graeme
