日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight and modulates gut peptide release--potential insight into mechanism of action

药理学抑制二酰甘油酰基转移酶 1 可减轻体重并调节肠道肽释放——对作用机制的潜在洞察

Jinqi Liu, Judith N Gorski, Stephen J Gold, Dunlu Chen, Shirley Chen, Gail Forrest, Yoshiki Itoh, Donald J Marsh, David G McLaren, Zhu Shen, Lisa Sonatore, Ester Carballo-Jane, Stephanie Craw, Xiaoming Guan, Bindhu Karanam, Junichi Sakaki, Daphne Szeto, Xinchun Tong, Jianying Xiao, Ryo Yoshimoto, Ho

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent

GPR40 部分激动剂和 AgoPAM:对啮齿动物葡萄糖和激素分泌的不同影响

Michele J Pachanski, Melissa E Kirkland, Daniel T Kosinski, Joel Mane, Boonlert Cheewatrakoolpong, Jiyan Xue, Daphne Szeto, Gail Forrest, Corin Miller, Michelle Bunzel, Christopher W Plummer, Harry R Chobanian, Michael W Miller, Sarah Souza, Brande S Thomas-Fowlkes, Aimie M Ogawa, Adam B Weinglass, 

Effects of carvedilol on structural and functional outcomes and plasma biomarkers in the mouse transverse aortic constriction heart failure model

卡维地洛对小鼠横主动脉缩窄性心力衰竭模型的结构和功能结果及血浆生物标志物的影响

Caryn Hampton, Raymond Rosa, Daphne Szeto, Gail Forrest, Barry Campbell, Richard Kennan, Shubing Wang, Chin-Hu Huang, Loise Gichuru, Xiaoli Ping, Xiaolan Shen, Kersten Small, Jeffrey Madwed, Joseph J Lynch

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey

siRNA 介导的 SCAP 抑制对小鼠和恒河猴 PCSK9、LDLR 和血浆脂质的剂量依赖性影响

Kristian K Jensen, Marija Tadin-Strapps, Sheng-Ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G McLaren, Stephen F Previs, Kithsiri B Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, S

Glucagon receptor antagonism induces increased cholesterol absorption

胰高血糖素受体拮抗剂可增加胆固醇吸收

Hong-Ping Guan, Xiaodong Yang, Ku Lu, Sheng-Ping Wang, Jose M Castro-Perez, Stephen Previs, Michael Wright, Vinit Shah, Kithsiri Herath, Dan Xie, Daphne Szeto, Gail Forrest, Jing Chen Xiao, Oksana Palyha, Li-Ping Sun, Paula J Andryuk, Samuel S Engel, Yusheng Xiong, Songnian Lin, David E Kelley, Mark

Potential mechanism of enhanced postprandial glucagon-like peptide-1 release following treatment with a diacylglycerol acyltransferase 1 inhibitor

二酰甘油酰基转移酶 1 抑制剂治疗后餐后胰高血糖素样肽-1 释放增强的潜在机制

Jinqi Liu, David G McLaren, Dunlu Chen, Yanqing Kan, Steven J Stout, Xiaolan Shen, Beth Ann Murphy, Gail Forrest, Bindhu Karanam, Lisa Sonatore, Shuwen He, Thomas P Roddy, Shirly Pinto

Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistance

磷酸二酯酶 10A 的基因缺失和药物抑制可保护小鼠免于饮食引起的肥胖和胰岛素抵抗

Andrea R Nawrocki, Carlos G Rodriguez, Dawn M Toolan, Olga Price, Melanie Henry, Gail Forrest, Daphne Szeto, Carol Ann Keohane, Yie Pan, Karen M Smith, Izzat T Raheem, Christopher D Cox, Joyce Hwa, John J Renger, Sean M Smith

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms

丁酸和丙酸可通过游离脂肪酸受体 3 独立机制预防饮食引起的肥胖并调节肠道激素

Hua V Lin, Andrea Frassetto, Edward J Kowalik Jr, Andrea R Nawrocki, Mofei M Lu, Jennifer R Kosinski, James A Hubert, Daphne Szeto, Xiaorui Yao, Gail Forrest, Donald J Marsh

Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension

盐皮质激素受体的慢性拮抗作用可改善啮齿动物盐敏感性高血压模型中的高血压和终末器官损伤

Xiaoyan Zhou, Martin F Crook, Wanda Sharif-Rodriguez, Yonghua Zhu, Zadok Ruben, Yi Pan, Olga Urosevic-Price, Li Wang, Amy M Flattery, Gail Forrest, Daphne Szeto, Huawei Zhao, Sophie Roy, Michael J Forrest