日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor

非共价 SARS-CoV-2 主要蛋白酶抑制剂的命中扩增

Jens Glaser, Ada Sedova, Stephanie Galanie, Daniel W Kneller, Russell B Davidson, Elvis Maradzike, Sara Del Galdo, Audrey Labbé, Darren J Hsu, Rupesh Agarwal, Dmytro Bykov, Arnold Tharrington, Jerry M Parks, Dayle M A Smith, Isabella Daidone, Leighton Coates, Andrey Kovalevsky, Jeremy C Smith

Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2

对SARS-CoV-2木瓜蛋白酶样蛋白酶的强效选择性共价抑制

Sanders, Brian; Pokhrel, Suman; Labbe, Audrey; Mathews, Irimpan; Cooper, Connor; Davidson, Russell; Phillips, Gwyndalyn; Weiss, Kevin; Zhang, Qiu; O'Neill, Hugh; Kaur, Manat; Ferrins, Lori; Schmidt, Jurgen; Reichard, Walter; Surendranathan, Surekha; Parvathareddy, Jyothi; Phillips, Lexi; Rainville, Christopher; Sterner, David; Kumaran, Desigan; Andi, Babak; Babnigg, Gyorgy; Moriarty, Nigel; Adams, Paul; Joachimiak, Andrzej; Hurst, Brett; Kumar, Suresh; Butt, Tauseef; Jonsson, Colleen; Wakatsuki, Soichi; Galanie, Stephanie; Head, Martha; Parks, Jerry

Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease

抑制剂与 SARS-CoV-2 主蛋白酶 S1 和 S2 亚位点结合的结构、电子和静电决定因素

Daniel W Kneller, Hui Li, Stephanie Galanie, Gwyndalyn Phillips, Audrey Labbé, Kevin L Weiss, Qiu Zhang, Mark A Arnould, Austin Clyde, Heng Ma, Arvind Ramanathan, Colleen B Jonsson, Martha S Head, Leighton Coates, John M Louis, Peter V Bonnesen, Andrey Kovalevsky

Malleability of the SARS-CoV-2 3CL Mpro Active-Site Cavity Facilitates Binding of Clinical Antivirals

SARS-CoV-2 3CL Mpro 活性位点腔体的可塑性有利于临床抗病毒药物的结合

Daniel W Kneller, Stephanie Galanie, Gwyndalyn Phillips, Hugh M O'Neill, Leighton Coates, Andrey Kovalevsky

Complete biosynthesis of opioids in yeast

酵母中阿片类药物的完全生物合成

Galanie, Stephanie; Thodey, Kate; Trenchard, Isis J; Filsinger Interrante, Maria; Smolke, Christina D

Optimization of yeast-based production of medicinal protoberberine alkaloids

酵母生产药用原小檗碱生物碱的优化

Stephanie Galanie, Christina D Smolke

A microbial biomanufacturing platform for natural and semisynthetic opioids

天然和半合成阿片类药物的微生物生物制造平台

Kate Thodey, Stephanie Galanie, Christina D Smolke

Molecular tools for chemical biotechnology

用于化学生物技术的分子工具

Galanie, Stephanie; Siddiqui, Michael S; Smolke, Christina D