An Nlrp5-null mutation leads to attenuated de novo methylation in oocytes, accompanied by a significant reduction in DNMT3L.
Nlrp5 缺失突变导致卵母细胞中从头甲基化减弱,同时 DNMT3L 显著减少。
期刊:Molecular Human Reproduction
影响因子:3.5
doi:10.1093/molehr/gaaf055
Nic Aodha Leah, Pokhilko Alexandra, Rosen Leah U, Galatidou Styliani, Walewska Edyta, Belton Christian, Galvao Antonio, Okkenhaug Hanneke, Yu Lu, Nakhuda Asif, Mansfield Bill, Khan Soumen, Oxley David, Barragán Montserrat, Kelsey Gavin