日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Population Physiologically-Based Pharmacokinetic Modeling to Determine Ontogeny: A Quantitative Clinical Pharmacology Example in Pediatric Rare Disease

基于群体生理的药代动力学模型确定个体发育：儿科罕见病定量临床药理学实例

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70174
Cleary, Yumi; Prasad, Bhagwat; Ogungbenro, Kayode; Gertz, Michael; Galetin, Aleksandra
发育与干细胞
发表日期：2026
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Predicting OCT2/MATEs-Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

预测健康志愿者和慢性肾病患者中 OCT2/MATEs 介导的药物相互作用：来自延长清除概念、内源性生物标志物和体外抑制研究的见解（国际转运体联盟的观点）

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.3727
Asano, Satoshi; Galetin, Aleksandra; Tomita, Yoshiko; Giacomini, Kathleen M; Chu, Xiaoyan; Yang, Xinning; Nakamura, Toshimichi; Kusuhara, Hiroyuki; Sugiyama, Yuichi
发表日期：2025
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Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase-CYP substrates

建立醛氧化酶和双重醛氧化酶-CYP底物的生理药代动力学框架

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13255
Izat, Nihan; Bolleddula, Jayaprakasam; Carione, Pasquale; Huertas Valentin, Leticia; Jones, Robert S; Kulkarni, Priyanka; Moss, Darren; Peterkin, Vincent C; Tian, Dan-Dan; Treyer, Andrea; Venkatakrishnan, Karthik; Zientek, Michael A; Barber, Jill; Houston, J Brian; Galetin, Aleksandra; Scotcher, Daniel
发表日期：2025
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Evaluation of Adefovir PBPK Model to Assess Biomarker-Informed OAT1 Drug-Drug Interaction and Effect of Chronic Kidney Disease

利用生物标志物指导的阿德福韦PBPK模型评估OAT1药物相互作用及慢性肾脏病的影响

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70010
Tan, Shawn Pei Feng; Wu, Huaying; Rostami-Hodjegan, Amin; Scotcher, Daniel; Galetin, Aleksandra
OAT
发表日期：2025
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Genotype, Ethnicity, and Drug-Drug Interaction Modeling as Means of Verifying Transporter Biomarker PBPK Model: The Coproporphyrin-I Story

基因型、种族和药物相互作用建模作为验证转运体生物标志物PBPK模型的方法：以粪卟啉-I为例

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70008
Ujihira, Yuki; Tan, Shawn Pei Feng; Scotcher, Daniel; Galetin, Aleksandra
发表日期：2025
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Membrane transporters in drug development and as determinants of precision medicine

膜转运蛋白在药物研发中的作用以及作为精准医疗的决定因素

期刊:Nature Reviews Drug Discovery
影响因子:101.8
doi:10.1038/s41573-023-00877-1
Galetin, Aleksandra; Brouwer, Kim L R; Tweedie, Donald; Yoshida, Kenta; Sjöstedt, Noora; Aleksunes, Lauren; Chu, Xiaoyan; Evers, Raymond; Hafey, Michael J; Lai, Yurong; Matsson, Pär; Riselli, Andrew; Shen, Hong; Sparreboom, Alex; Varma, Manthena V S; Yang, Jia; Yang, Xinning; Yee, Sook Wah; Zamek-Gliszczynski, Maciej J; Zhang, Lei; Giacomini, Kathleen M
发表日期：2024
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Albumin-Mediated Drug Uptake by Organic Anion Transporter 1/3 Is Real: Implications for the Prediction of Active Renal Secretion Clearance

有机阴离子转运体 1/3 介导白蛋白药物吸收是真实存在的：对预测主动肾分泌清除率的意义

期刊:Molecular Pharmaceutics
影响因子:3.2
doi:10.1021/acs.molpharmaceut.4c00504
Shawn Pei Feng Tan, Annika Tillmann, Susan J Murby, Amin Rostami-Hodjegan, Daniel Scotcher, Aleksandra Galetin
发表日期：2024
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A close examination of BCRP's role in lactation and methods for predicting drug distribution into milk

对BCRP在泌乳中的作用以及预测药物在乳汁中分布的方法进行深入研究

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13243
Sychterz, Caroline; Shen, Hong; Zhang, Yueping; Sinz, Michael; Rostami-Hodjegan, Amin; Schmidt, Brian J; Gaohua, Lu; Galetin, Aleksandra
BCR
CRP
发表日期：2024
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Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in Rats

利用体内成像和基于生理学的动力学模型预测大鼠肝脏转运蛋白介导的药物相互作用

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics15030896
Melillo, Nicola; Scotcher, Daniel; Kenna, J Gerry; Green, Claudia; Hines, Catherine D G; Laitinen, Iina; Hockings, Paul D; Ogungbenro, Kayode; Gunwhy, Ebony R; Sourbron, Steven; Waterton, John C; Schuetz, Gunnar; Galetin, Aleksandra
Rat
发表日期：2023
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Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug-Drug Interactions in Children

利用利司他林机制群体药代动力学模型估算FMO3发育及其对儿童药物相互作用的影响

期刊:Clinical Pharmacokinetics
影响因子:4
doi:10.1007/s40262-023-01241-7
Cleary, Yumi; Kletzl, Heidemarie; Grimsey, Paul; Heinig, Katja; Ogungbenro, Kayode; Silber Baumann, Hanna Elisabeth; Frey, Nicolas; Aarons, Leon; Galetin, Aleksandra; Gertz, Michael
发育与干细胞
发表日期：2023
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