日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis

PKC 对 PP2Ac 的磷酸化是 PP2A 开关依赖性 AKT 去磷酸化的关键调节步骤,可导致细胞凋亡

Guy Nadel #, Zhong Yao #, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Tamar Ziv, Zvi Naor, Arie Admon, Rony Seger

GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch

GqPCR 刺激的 AKT 去磷酸化是由 IGBP1 介导的 PP2A 开关诱导的

Guy Nadel #, Zhong Yao #, Ehud Wainstein #, Izel Cohen, Ido Ben-Ami, Amir Schajnovitz, Galia Maik-Rachline, Zvi Naor, Benjamin A Horwitz, Rony Seger

AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope

AKT 在受到刺激时不会转位到细胞核,但 AKT3 可以从核膜持续发出信号

Ehud Wainstein, Galia Maik-Rachline, John Blenis, Rony Seger

Applying imaging flow cytometry and immunofluorescence in studying the dynamic Golgi structure in cultured cells

应用成像流式细胞术和免疫荧光研究培养细胞中的动态高尔基结构

Inbal Wortzel, Ziv Porat, Rony Seger, Galia Maik-Rachline

Mitotic HOOK3 phosphorylation by ERK1c drives microtubule-dependent Golgi destabilization and fragmentation

ERK1c介导的HOOK3磷酸化导致微管依赖性的高尔基体不稳定和碎裂

Inbal Wortzel,Galia Maik-Rachline,Suresh Singh Yadav,Tamar Hanoch,Rony Seger

Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases

内在活性 MEK 变体受蛋白酶和磷酸酶的不同调控

Merav Ordan, Chiara Pallara, Galia Maik-Rachline, Tamar Hanoch, Francesco Luigi Gervasio, Fabian Glaser, Juan Fernandez-Recio, Rony Seger

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells

MEK 和核 ERK 易位的联合抑制在黑色素瘤细胞中具有协同抗肿瘤活性

Rand Arafeh, Karen Flores, Alona Keren-Paz, Galia Maik-Rachline, Naomi Gutkind, Steven Rosenberg, Rony Seger, Yardena Samuels

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

蛋白偶联受体 37 是少突胶质细胞分化和髓鞘形成的负调节剂

Hyun-Jeong Yang, Anna Vainshtein, Galia Maik-Rachline, Elior Peles