The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat.
情绪稳定剂锂和丙戊酸盐会扰乱肝脏和肠道的法尼醇X受体信号传导,并增加大鼠的胆汁合成
期刊:Experimental Physiology
影响因子:2.8
doi:10.1113/EP092451
Cussotto Sofia, Golubeva Anna V, Gallardo Alvaro Lopez, Bastiaanssen Thomaz F S, Zhdanov Alexander V, Moloney Gerard M, Scaife Caitriona, English Jane A, Joyce Susan A, Dinan Timothy G, Cryan John F