日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

STING agonist-containing microparticles improve seasonal influenza vaccine efficacy and durability in ferrets over standard adjuvant

含 STING 激动剂的微粒比标准佐剂更能提高雪貂季节性流感疫苗的有效性和持久性

Matthew D Gallovic, Robert D Junkins, Adam M Sandor, Erik S Pena, Christopher J Sample, Ariel K Mason, Leslee C Arwood, Rebecca A Sahm, Eric M Bachelder, Kristy M Ainslie, Gregory D Sempowski, Jenny P-Y Ting

A predictive mechanistic model of drug release from surface eroding polymeric nanoparticles

表面侵蚀聚合物纳米粒子药物释放的预测机械模型

Rebeca T Stiepel, Erik S Pena, Stephen A Ehrenzeller, Matthew D Gallovic, Liubov M Lifshits, Christopher J Genito, Eric M Bachelder, Kristy M Ainslie

Multiplexed electrospray enables high throughput production of cGAMP microparticles to serve as an adjuvant for a broadly acting influenza vaccine

多重电喷雾技术可实现cGAMP微粒的高通量生产,该微粒可用作广谱流感疫苗的佐剂。

Cole J Batty ,Matthew D Gallovic ,Jonathan Williams ,Ted M Ross ,Eric M Bachelder ,Kristy M Ainslie

STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways

STING 激动剂通过刺激 I 型 IFN 依赖性和 I 型 IFN 非依赖性免疫调节通路缓解实验性自身免疫性脑脊髓炎

Brandon M Johnson, Toru Uchimura, Matthew D Gallovic, Madhan Thamilarasan, Wei-Chun Chou, Sara A Gibson, Meng Deng, Jason W Tam, Cole J Batty, Jonathan Williams, Glenn K Matsushima, Eric M Bachelder, Kristy M Ainslie, Silva Markovic-Plese, Jenny P-Y Ting

A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8+ T cell-mediated anti-tumor immunity

一种用于STING靶向免疫疗法的微粒平台可增强自然杀伤细胞和CD8+ T细胞介导的抗肿瘤免疫力。

Rebekah Watkins-Schulz ,Pamela Tiet ,Matthew D Gallovic ,Robert D Junkins ,Cole Batty ,Eric M Bachelder ,Kristy M Ainslie ,Jenny P Y Ting

Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo

电喷雾技术用于生成药物递送和疫苗颗粒,该技术已应用于体外和体内研究。

Steipel, Rebeca T; Gallovic, Matthew D; Batty, Cole J; Bachelder, Eric M; Ainslie, Kristy M

Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy

研究可调乙酰葡聚糖微粒平台以优化基于 M2e 的流感疫苗功效

Naihan Chen, Matthew D Gallovic, Pamela Tiet, Jenny P-Y Ting, Kristy M Ainslie, Eric M Bachelder

Tunable degradation of acetalated dextran microparticles enables controlled vaccine adjuvant and antigen delivery to modulate adaptive immune responses

乙酰化葡聚糖微粒的可调降解可实现对疫苗佐剂和抗原的可控输送,从而调节适应性免疫反应

Naihan Chen, Monica M Johnson, Michael A Collier, Matthew D Gallovic, Eric M Bachelder, Kristy M Ainslie

A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination

一种针对 STING 的佐剂的强大微粒平台,可在疫苗接种期间增强体液和细胞免疫力

Robert D Junkins, Matthew D Gallovic, Brandon M Johnson, Michael A Collier, Rebekah Watkins-Schulz, Ning Cheng, Clément N David, Charles E McGee, Gregory D Sempowski, Ivo Shterev, Karen McKinnon, Eric M Bachelder, Kristy M Ainslie, Jenny P-Y Ting

Injectable long-acting human immunodeficiency virus antiretroviral prodrugs with improved pharmacokinetic profiles.

具有改进的药代动力学特性的可注射长效人类免疫缺陷病毒抗逆转录病毒前药

Krovi Sai Archana, Gallovic Matthew D, Keller Austin M, Bhat Menakshi, Tiet Pamela, Chen Naihan, Collier Michael A, Gurysh Elizabeth G, Pino Erica N, Johnson Monica M, Shamim Hasan Zahid M, Cottrell Mackenzie L, Pirone Jason R, Kashuba Angela D, Kwiek Jesse J, Bachelder Eric M, Ainslie Kristy M