日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Monitoring biological effects of somatic cell genome editing

监测体细胞基因组编辑的生物学效应

Freedman, Benjamin S; Bulte, Jeff W M; Conklin, Bruce R; Judge, Luke M; Dwinell, Melinda R; Geurts, Aron M; Sitton, Madeleine J; Mahajan, Vineet; Kiani, Samira; Gersbach, Charles A; Ebrahimkhani, Mo R; Kelly, John J; Ronald, John A; Morizane, Ryuji; Gupta, Navin; Shakeri-Zadeh, Ali; Vo, Nicole; Saha, Krishanu; Saxena, Shivani; Gamm, David M; Sinha, Divya; Tarantal, Alice F; Vandsburger, Moriel; Matsubara, Azusa; Fu, Hongxia; Tsai, Shengdar Q

A porcine commotio retinae model for preclinical evaluation of posttraumatic photoreceptor degeneration.

猪视网膜震荡模型用于创伤后感光细胞变性的临床前评估。

Amaral Juan, Bunea Irina, Maminishkis Arvydas, Campos Maria M, Barone Francesca, Gupta Rohan, Farnoodian Mitra, Newport Jonathan, Phillips M Joseph, Sharma Ruchi, Gamm David M, Bharti Kapil, Blanch Richard J

Comprehensive promotion of iPSC-CM maturation by integrating metabolic medium with nanopatterning and electrostimulation

通过将代谢培养基与纳米图案化和电刺激相结合,全面促进iPSC-CM成熟

Wener Li ,Xiaojing Luo ,Anna Strano ,Shakthi Arun ,Oliver Gamm ,Mareike S Poetsch ,Marcel Hasse ,Robert-Patrick Steiner ,Konstanze Fischer ,Jessie Pöche ,Ying Ulbricht ,Mathias Lesche ,Giulia Trimaglio ,Ali El-Armouche ,Andreas Dahl ,Peter Mirtschink ,Kaomei Guan ,Mario Schubert

Metabolic stress and early cell death in photoreceptor precursor cells following retinal transplantation

视网膜移植后感光细胞前体细胞的代谢应激和早期细胞死亡

Sudharsan, Raghavi; Dolgova, Natalia; Kwok, Jennifer; Gray, Alexa; Sato, Yu; Madrigal, Agustin Luz; Susaimanickam, Praveen Joseph; Kriukov, Emil; Baranov, Petr; Wolfe, John H; Aguirre, Gustavo D; Gamm, David M; Beltran, William A

Selective Modification of the Product Profile of Biocatalytic Hydrolyzed PET via Product-Specific Medium Engineering

通过产品特异性介质工程选择性地修饰生物催化水解PET的产品特性

Heinks, Tobias; Hofmann, Katrin; Last, Simon; Gamm, Igor; Blach, Luise; Wei, Ren; Bornscheuer, Uwe T; Hamel, Christof; von Langermann, Jan

Robust generation of photoreceptor-dominant retinal organoids from porcine induced pluripotent stem cells

利用猪诱导多能干细胞高效生成以感光细胞为主的视网膜类器官

Edwards, Kimberly L; Moore, Bethany M; Ganser, Tyler-Serie; Susaimanickam, Praveen Joseph; Sovell, Kai; Martin, Yolana; Jager, Lindsey D; Willes, Ashley M; Moyer, Tyra H; Bowar, Lydia; Phillips, M Joseph; Stewart, Ron; Chu, Li-Fang; Gamm, David M

Non-invasive maturity assessment of iPSC-CMs based on optical maturity characteristics using interpretable AI

基于光学成熟特征和可解释人工智能的非侵入性iPSC-CM成熟度评估方法,用于评估iPSC-CMs的成熟度,该方法基于光学成熟度特征,并利用人工智能进行分析。

Scheurer, Fabian; Hammer, Alexander; Schubert, Mario; Steiner, Robert-Patrick; Gamm, Oliver; Guan, Kaomei; Sonntag, Frank; Malberg, Hagen; Schmidt, Martin

The need to adapt after Alzheimer's disease diagnosis: Coping strategies used to maintain identity and quality of life

确诊阿尔茨海默病后需要适应:维持自我认同和生活质量的应对策略

Gamm, Simone; Ummel, Deborah; Vasil, Nancy; Grenier, Sébastien

AAV2.7m8 transduction of stage 2 human retinal organoids induces highly variable responses in innate and inflammatory gene expression and cytokine secretion

AAV2.7m8 转导第二阶段人类视网膜类器官可诱导先天性和炎症基因表达以及细胞因子分泌方面的高度可变反应。

Monica M Sauter,Hongyu Rao Noel,Divya Sinha,Emma C Nelson,Mai N Xiong,David M Gamm,Curtis R Brandt

Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.

在小鼠和猪动物模型中对视网膜下注射的 Cas9 核糖核蛋白进行评估,突显了基因药物治疗转化中的关键考虑因素

Wei Spencer C, Cantor Aaron J, Walleshauser Jack, Mepani Rina, Melton Kory, Bans Ashil, Khekare Prachi, Gupta Suhani, Wang Jonathan, Soares Craig, Kiwan Radwan, Lee Jieun, McCawley Shannon, Jani Vihasi, Leong Weng In, Shahi Pawan K, Chan Jean, Boivin Pierre, Otoupal Peter, Pattnaik Bikash R, Gamm David M, Saha Krishanu, Gowen Benjamin G, Haak-Frendscho Mary, Janatpour Mary J, Silverman Adam P