日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia

靶向 S100A9 蛋白会影响 mTOR-ER 应激信号并增加急性髓系白血病对维奈克拉的敏感性

Rong Fan, Hatice Satilmis, Niels Vandewalle, Emma Verheye, Elke De Bruyne, Eline Menu, Nathan De Beule, Ann De Becker, Gamze Ates, Ann Massie, Tessa Kerre, Marie Törngren, Helena Eriksson, Karin Vanderkerken, Karine Breckpot, Ken Maes, Kim De Veirman2

Pancreatic acinar cell fate relies on system xC- to prevent ferroptosis during stress

胰腺腺泡细胞的命运依赖于 xC 系统来防止应激期间的铁死亡

Zhaolong Pan, Jan-Lars Van den Bossche, Eva Rodriguez-Aznar, Pauline Janssen, Olaya Lara, Gamze Ates, Ann Massie, Diedert Luc De Paep, Isabelle Houbracken, Marco Mambretti #, Ilse Rooman #

Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism

以 β2 肾上腺素受体为靶点,通过诱导细胞凋亡和调节癌细胞代谢来增加多发性骨髓瘤的化学敏感性

Hatice Satilmis, Emma Verheye, Philip Vlummens, Inge Oudaert, Niels Vandewalle, Rong Fan, Jennifer M Knight, Nathan De Beule, Gamze Ates, Ann Massie, Jerome Moreaux, Anke Maes, Elke De Bruyne, Karin Vanderkerken, Eline Menu, Erica K Sloan, Kim De Veirman

AMPKα1 Deficiency in Astrocytes from a Rat Model of ALS Is Associated with an Altered Metabolic Resilience

大鼠 ALS 模型中星形胶质细胞的 AMPKα1 缺乏与代谢弹性改变有关

Inês Belo do Nascimento, Gamze Ates, Nathalie Desmet, Pauline Beckers, Ann Massie, Emmanuel Hermans

Lifespan extension with preservation of hippocampal function in aged system xc--deficient male mice

延长寿命并保留老年系统 xc 缺陷雄性小鼠的海马功能

Lise Verbruggen #, Gamze Ates #, Olaya Lara, Jolien De Munck, Agnès Villers, Laura De Pauw, Sigrid Ottestad-Hansen, Sho Kobayashi, Pauline Beckers, Pauline Janssen, Hideyo Sato, Yun Zhou, Emmanuel Hermans, Rose Njemini, Lutgarde Arckens, Niels C Danbolt, Dimitri De Bundel, Joeri L Aerts, Kurt Barbé,

AMPK Modulates the Metabolic Adaptation of C6 Glioma Cells in Glucose-Deprived Conditions without Affecting Glutamate Transport

AMPK 调节 C6 胶质瘤细胞在缺糖条件下的代谢适应,而不影响谷氨酸转运

Inês Belo do Nascimento, Marie Verfaillie, Gamze Ates, Pauline Beckers, Virginie Joris, Nathalie Desmet, Ann Massie, Emmanuel Hermans

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

CMS121 是一种脂肪酸合酶抑制剂,可防止过量脂质过氧化和炎症,并减轻阿尔茨海默病转基因小鼠模型的认知能力丧失

Gamze Ates, Joshua Goldberg, Antonio Currais, Pamela Maher

Targeting of intracellular Ca2+ stores as a therapeutic strategy against age-related neurotoxicities

以细胞内 Ca2+ 库为目标作为对抗年龄相关性神经毒性的治疗策略

Joshua Goldberg, Antonio Currais, Gamze Ates, Ling Huang, Maxim Shokhirev, Pamela Maher, David Schubert

Elevating acetyl-CoA levels reduces aspects of brain aging

提高乙酰辅酶 A 水平可减缓大脑衰老

Antonio Currais, Ling Huang, Joshua Goldberg, Michael Petrascheck, Gamze Ates, António Pinto-Duarte, Maxim N Shokhirev, David Schubert, Pamela Maher

Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes

使用人类诱导多能干细胞衍生的心肌细胞对化妆品化合物进行功能性心脏毒性评估

Umesh Chaudhari, Harshal Nemade, Poornima Sureshkumar, Mathieu Vinken, Gamze Ates, Vera Rogiers, Jürgen Hescheler, Jan Georg Hengstler, Agapios Sachinidis