Gan Li-Ming相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

RNA interference therapy targeting coagulation factor XI: a first-in-human trial of RBD4059 (vortosiran)

靶向凝血因子XI的RNA干扰疗法：RBD4059（vortosiran）的首次人体试验

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2025018348

Gabrielsen, Anders; Ueckert, Sebastian; Nilsson, Catarina; Egnell, Ann-Charlotte; Fu, Jing; Wikström, Johannes; Svedlund, Sara; Friend, Richard; Zhang, Hongyan; Liang, Zicai; Gao, Shan; Gan, Li-Ming

发表日期：2026

文献求助收藏

Inhibition of Factor XI Using RBD4059: A Novel GalNAc-siRNA With Potent and Durable Antithrombotic Effects

利用RBD4059抑制因子XI：一种新型GalNAc-siRNA具有强效且持久的抗血栓作用

期刊:Jacc-Basic To Translational Science

影响因子:7.2

doi:10.1016/j.jacbts.2024.12.005

Liang, Junshi; Nilsson, Sofia; Wikström, Johannes; Cao, Huiqing; Zheng, Shuquan; Xu, Qian; Yan, Xu; Ueckert, Sebastian; Sun, Qi; Guo, Chun; Zhang, Hongyan; Liang, Zicai; Gao, Shan; Gan, Li-Ming

发表日期：2025

文献求助收藏

A potent GalNAc-siRNA drug, RBD1016, leads to sustained HBsAg reduction and seroconversion in mouse models of HBV infection

一种强效的 GalNAc-siRNA 药物 RBD1016 可导致 HBV 感染小鼠模型中 HBsAg 持续降低和血清转化。

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.1

doi:10.1016/j.omtn.2025.102627

Zheng, Shuquan; Cao, Huiqing; Zhang, Min; Guo, Chun; Yan, Xu; Sun, Qi; Zhang, Hongyan; Liang, Zicai; Gao, Shan; Gan, Li-Ming

发表日期：2025

文献求助收藏

SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signaling

SGLT2抑制剂可改善冠状动脉血流速度储备和收缩力：胰高血糖素信号传导的作用

期刊:Cardiovascular Diabetology

影响因子:10.6

doi:10.1186/s12933-024-02491-w

Göpel, Sven O; Adingupu, Damilola; Wang, Jue; Semenova, Elizaveta; Behrendt, Margareta; Jansson-Löfmark, Rasmus; Ahlström, Christine; Jönsson-Rylander, Ann-Cathrine; Gopaul, V Sashi; Esterline, Russell; Gan, Li-Ming; Xiao, Rui-Ping

发表日期：2024

文献求助收藏

External validation of a deep learning algorithm for automated echocardiographic strain measurements

对用于自动超声心动图应变测量的深度学习算法进行外部验证

期刊:European Heart Journal - Digital Health

影响因子:3.9

doi:10.1093/ehjdh/ztad072

Myhre, Peder L; Hung, Chung-Lieh; Frost, Matthew J; Jiang, Zhubo; Ouwerkerk, Wouter; Teramoto, Kanako; Svedlund, Sara; Saraste, Antti; Hage, Camilla; Tan, Ru-San; Beussink-Nelson, Lauren; Fermer, Maria L; Gan, Li-Ming; Hummel, Yoran M; Lund, Lars H; Shah, Sanjiv J; Lam, Carolyn S P; Tromp, Jasper

发表日期：2024

文献求助收藏

Cardiometabolic biomarker patterns associated with cardiac MRI defined fibrosis and microvascular dysfunction in patients with heart failure with preserved ejection fraction

与心脏磁共振成像定义的射血分数保留型心力衰竭患者的纤维化和微血管功能障碍相关的心血管代谢生物标志物模式

期刊:Frontiers in Cardiovascular Medicine

影响因子:2.9

doi:10.3389/fcvm.2024.1334226

Siggins, Connor; Pan, Jonathan A; Löffler, Adrián I; Yang, Yang; Shaw, Peter W; Balfour, Pelbreton C Jr; Epstein, Frederick H; Gan, Li-Ming; Kramer, Christopher M; Keeley, Ellen C; Salerno, Michael

发表日期：2024

文献求助收藏

ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study

ISIS 449884注射剂作为二甲双胍的附加疗法用于2型糖尿病患者：一项随机、双盲、安慰剂对照的II期临床研究

期刊:Diabetes Therapy

影响因子:2.6

doi:10.1007/s13300-024-01617-3

Ji, Linong; Gao, Leili; Feng, Zhikai; Chen, Guoliang; Fu, Jing; Morgan, Erin; Bhanot, Sanjay; Gao, Shan; Zhang, Hongyan; Liang, Zicai; Gan, Li-Ming

发表日期：2024

文献求助收藏

Publisher Correction to: ISIS 449884 Injection Add‑On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double‑Blind, Placebo‑Controlled, Phase II Clinical Study

出版商更正：ISIS 449884 二甲双胍注射剂辅助治疗2型糖尿病患者：一项随机、双盲、安慰剂对照的II期临床研究

期刊:Diabetes Therapy

影响因子:2.6

doi:10.1007/s13300-024-01633-3

Ji, Linong; Gao, Leili; Feng, Zhikai; Chen, Guoliang; Fu, Jing; Morgan, Erin; Bhanot, Sanjay; Gao, Shan; Zhang, Hongyan; Liang, Zicai; Gan, Li-Ming

发表日期：2024

文献求助收藏

Safety and Feasibility Using a Fluid-Filled Wire to Avoid Hydrostatic Errors in Physiological Intracoronary Measurements

使用充液导丝避免生理性冠状动脉内测量中的静水压误差的安全性和可行性

期刊:Cardiology Research and Practice

影响因子:1.8

doi:10.1155/2024/6664482

Råmunddal, Truls; Dworeck, Christian; Torild, Petronella; Andréen, Sofie; Gan, Li-Ming; Hirlekar, Geir; Ioanes, Dan; Myredal, Anna; Odenstedt, Jacob; Petursson, Petur; Pylova, Tetiana; Töpel, Fanny; Völz, Sebastian; Hilmersson, Mats; Redfors, Björn; Angerås, Oskar

发表日期：2024

文献求助收藏

Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting

对接受冠状动脉旁路移植术的患者进行心肌内直接注射VEGF mRNA

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2022.11.017

Anttila, Vesa; Saraste, Antti; Knuuti, Juhani; Hedman, Marja; Jaakkola, Pekka; Laugwitz, Karl-Ludwig; Krane, Markus; Jeppsson, Anders; Sillanmäki, Saara; Rosenmeier, Jaya; Zingmark, Pernilla; Rudvik, Anna; Garkaviy, Pavlo; Watson, Christina; Pangalos, Menelas N; Chien, Kenneth R; Fritsche-Danielson, Regina; Collén, Anna; Gan, Li-Ming

发表日期：2023

文献求助收藏