日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Hepatoprotective drug screening identifies daclatasvir, a promising therapeutic candidate for MASLD by targeting PLIN2

肝保护药物筛选发现达克拉他韦，这是一种通过靶向 PLIN2 治疗 MASLD 的潜在候选药物。

期刊:Journal of Lipid Research
影响因子:5
doi:10.1016/j.jlr.2025.100835
Rui Shu ,Song Tian ,Weiyi Qu ,Jinjie Yang ,Wei Shi ,Xinyan Li ,Toujun Zou ,Changjin Jiang ,Yuxuan Zhang ,Zifeng Yang ,Han Tian ,Hailong Yang ,Jiajun Fu ,Zhi-Gang She ,Hongliang Li ,Xiao-Jing Zhang
发表日期：2025
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Multispecies transcriptomics identifies SIKE as a MAPK repressor that prevents NASH progression

多物种转录组学鉴定出 SIKE 是一种 MAPK 抑制剂，可阻止 NASH 进展

期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.ade7347
Lan Bai, Weiyi Qu, Xu Cheng, Hailong Yang, Yong-Ping Huang, Zhenya Wang, Cuijuan Han, Rui-Feng Tian, Fengjiao Hu, Ling Yang, Song Tian, Han Tian, Zhiwei Cai, Juan Wan, Jingwei Jiang, Jiajun Fu, Junjie Zhou, Yufeng Hu, Tengfei Ma, Xin Zhang, Yan-Xiao Ji, Jingjing Cai, Zhi-Gang She, Yibin Wang, Peng Z
信号转导
MAPK/ERK
发表日期：2024
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MGMT activated by Wnt pathway promotes cisplatin tolerance through inducing slow-cycling cells and nonhomologous end joining in colorectal cancer.

Wnt 通路激活的 MGMT 通过诱导结直肠癌细胞的慢周期性增殖和非同源末端连接来促进顺铂耐受性

期刊:Journal of Pharmaceutical Analysis
影响因子:8.9
doi:10.1016/j.jpha.2024.02.004
Zhang Haowei, Li Qixin, Guo Xiaolong, Wu Hong, Hu Chenhao, Liu Gaixia, Yu Tianyu, Hu Xiake, Qiu Quanpeng, Guo Gang, She Junjun, Chen Yinnan
细胞生物学
肠癌
发表日期：2024
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Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD

组蛋白去甲基化酶KDM1A通过增加染色质可及性促进非酒精性脂肪性肝病（NAFLD）中的肝脂肪变性和炎症。

期刊:Journal of Lipid Research
影响因子:5
doi:10.1016/j.jlr.2024.100513
Zifeng Yang ,Siyao Zhang ,Xiang Liu ,Rui Shu ,Wei Shi ,Weiyi Qu ,Dianyu Liu ,Zhiwei Cai ,Ye Wang ,Xu Cheng ,Yemao Liu ,Xiao-Jing Zhang ,Lan Bai ,Hongliang Li ,Zhi-Gang She
炎症/感染
KDM1A
脂肪肝
炎症
表观遗传
发表日期：2024
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Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunction

Hippo 通路激活通过引起线粒体损伤和功能障碍介导化疗引起的抗癌作用和心肌病

期刊:Theranostics
影响因子:12.4
doi:10.7150/thno.79227
Gang She, Jin-Chan Du, Wei Wu, Tian-Tian Pu, Yu Zhang, Ru-Yue Bai, Yi Zhang, Zheng-Da Pang, Hui-Fang Wang, Yu-Jie Ren, Junichi Sadoshima, Xiu-Ling Deng, Xiao-Jun Du
肿瘤
心肌病
Hippo
发表日期：2023
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Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts

Nogo-B 介导内皮氧化应激和炎症，促进压力超负荷小鼠心脏的冠状动脉粥样硬化

期刊:Redox Biology
影响因子:10.7
doi:10.1016/j.redox.2023.102944
Yu Zhang, Jing-Jing Li, Rui Xu, Xin-Pei Wang, Xin-Yi Zhao, Yuan Fang, Yu-Peng Chen, Shan Ma, Xiao-Hui Di, Wei Wu, Gang She, Zheng-Da Pang, Yi-Dong Wang, Xing Zhang, Wenjun Xie, Xiu-Ling Deng, Xiao-Jun Du, Yi Zhang
信号转导
心血管
动脉粥样硬化
Mouse
发表日期：2023
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Honokiol acts as an AMPK complex agonist therapeutic in non-alcoholic fatty liver disease and metabolic syndrome

和厚朴酚可作为 AMPK 复合物激动剂治疗非酒精性脂肪肝和代谢综合征

期刊:Chinese Medicine
影响因子:5.3
doi:10.1186/s13020-023-00729-5
Ruifeng Tian #, Jinjie Yang #, Xiaoming Wang, Shuaiyang Liu, Ruixiang Dong, Zhenya Wang, Zifeng Yang, Yingping Zhang, Zhiwei Cai, Hailong Yang, Yufeng Hu, Zhi-Gang She, Hongliang Li, Junjie Zhou, Xiao-Jing Zhang
代谢
脂肪肝
IHC
Goat
IgG Fc
发表日期：2023
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A high-throughput drug screening identifies luteolin as a therapeutic candidate for pathological cardiac hypertrophy and heart failure

高通量药物筛选确定木犀草素是病理性心脏肥大和心力衰竭的治疗候选药物

期刊:Frontiers in Cardiovascular Medicine
影响因子:2.8
doi:10.3389/fcvm.2023.1130635
Zhenya Wang, Wei Shi, Taibo Wu, Tian Peng, Xiaoming Wang, Shuaiyang Liu, Zifeng Yang, Jia Wang, Peng-Long Li, Ruifeng Tian, Ying Hong, Hailong Yang, Lan Bai, Yufeng Hu, Xu Cheng, Hongliang Li, Xiao-Jing Zhang, Zhi-Gang She
心血管
心力衰竭
发表日期：2023
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A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis

激酶组筛选显示 Nemo 样激酶是肝糖异生的关键抑制剂

期刊:Cell Metabolism
影响因子:27.7
doi:10.1016/j.cmet.2021.04.006
Yan-Xiao Ji, Yutao Wang, Peng-Long Li, Lin Cai, Xiao-Ming Wang, Lan Bai, Zhen Liu, Han Tian, Song Tian, Peng Zhang, Xiao-Jing Zhang, Xu Cheng, Yufeng Yuan, Zhi-Gang She, Yufeng Hu, Hongliang Li
信号转导
发表日期：2021
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Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis

多项组学研究确定了非酒精性脂肪性肝炎的跨物种保守驱动因素

期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.abg8117
Xiao-Jing Zhang, Zhi-Gang She, Junyong Wang, Dating Sun, Li-Jun Shen, Hui Xiang, Xu Cheng, Yan-Xiao Ji, Yong-Ping Huang, Peng-Long Li, Xia Yang, Yanjie Cheng, Jun-Peng Ma, Hai-Ping Wang, Yufeng Hu, Fengjiao Hu, Song Tian, Han Tian, Peng Zhang, Guang-Nian Zhao, Lin Wang, Man-Li Hu, Qin Yang, Li-Hua Z
代谢
免疫
肝炎
发表日期：2021
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